© 2019

Critical Care Pediatric Nephrology and Dialysis: A Practical Handbook

  • Sidharth Kumar Sethi
  • Rupesh Raina
  • Mignon McCulloch
  • Timothy E. Bunchman

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Acute Kidney Injury in a Sick Child

    1. Front Matter
      Pages 1-1
    2. Neziha Celebi, Ayse Akcan Arikan
      Pages 3-10
    3. Eileen Ciccia, Prasad Devarajan
      Pages 11-18
  3. Managing a Sick Child with AKI

    1. Front Matter
      Pages 19-19
    2. Jitendra Meena, Arvind Bagga
      Pages 21-33
    3. Leyat Tal, Manpreet Kaur Virk, Ayse Akcan Arikan
      Pages 35-46
    4. Norma J. Maxvold, Timothy E. Bunchman
      Pages 47-55
    5. Joshua Zaritsky, Carl Gerdine
      Pages 57-65
  4. RRT in a Sick Child

    1. Front Matter
      Pages 67-67
    2. Mignon McCulloch, Sidharth Kumar Sethi, Ilana Webber, Peter Nourse
      Pages 69-85
    3. Deepa Chand, Rupesh Raina
      Pages 87-94
    4. Rupesh Raina, Vinod Krishnappa
      Pages 95-106
    5. Timothy E. Bunchman
      Pages 113-120
    6. Anna Maslach-Hubbard, Raoul Nelson, Jamie Furlong-Dillard
      Pages 121-135
  5. Special Situations

    1. Front Matter
      Pages 137-137
    2. Daniella Levy-Erez, Haewon C. Kim
      Pages 139-170
    3. Indrani Bhattacharjee, Marissa J. DeFreitas, Maroun Mhanna, Carolyn Abitbol
      Pages 171-186
    4. Sidharth Kumar Sethi
      Pages 187-194

About this book


This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children in intensive care.  

In addition, this quick guide discusses innovations in pediatric renal replacement therapy technologies, such as plasma exchange, CARPEDIEM, NIDUS and aquadex. 

This is a go-to book for intensivists, physicians and trainees working in pediatric intensive care units.



Pediatric intensive care Acute kidney injury Hemolytic uremic syndrome SLED and hybrid therapies CRRT Plasmapheresis in the PICU

Editors and affiliations

  • Sidharth Kumar Sethi
    • 1
  • Rupesh Raina
    • 2
  • Mignon McCulloch
    • 3
  • Timothy E. Bunchman
    • 4
  1. 1.Kidney & Urology InstituteMedanta, The Medicity Kidney & Urology InstituteGurugramIndia
  2. 2.Department of NephrologyCleveland Clinic Akron General Medical center and Akron Children’s HospitalAkronUSA
  3. 3.Red Cross War Memorial Children’s HospitalUniversity of Cape TownCape TownSouth Africa
  4. 4.Pediatric NephrologyChildren’s Hospital of Richmond at the Virginia Commonwealth UniversityRichmondUSA

About the editors

Dr. Sidharth Kumar Sethi is a Senior Consultant in Pediatric Nephrology and Pediatric Renal Transplant Medicine at the Kidney and Urology Institute, Medanta, India. He completed his fellowship (International Pediatric Nephrology Association Fellowship) and senior residency in Pediatric Nephrology at the All India Institute of Medical Sciences, New Delhi and the Division of Pediatric Nephrology and Transplant Immunology at Cedars Sinai Medical Centre, Los Angeles, California. He has been involved in numerous national and international meetings on pediatric acute kidney injury and pediatric dialysis. His chief interests include acute kidney injury, dialysis and pediatric renal transplantation. He has been actively involved in the care of children with all kinds of complex renal disorders, including acute kidney injury, nephrotic syndrome, tubular disorders, urinary tract infections, hypertension, chronic kidney disease. He was honored by Case Western Reserve University for his outstanding contributions to the field in 2014. He was part of an 8-member committee responsible for writing the Indian guidelines on steroid sensitive nephrotic syndrome, and member of an expert committee involved in the formulation of guidelines on pediatric renal disorders, including steroid resistant nephrotic syndrome and urinary tract infections. He has published several international papers on pediatric nephrology and chapters in nephrology textbooks. He is also Co-Convener of the Indian Society of Pediatric Nephrology- CKD Registry. He is currently Secretary of the Indian Society of Pediatric Nephrology and Editor of the Journal of Clinical Pediatric Nephrology'.  

Dr. Rupesh Raina MD, FACP, FAAP, FASN and FNKF is an Associate Professor and currently a combined Adult and Pediatric Nephrologist, Director of Medical Research in Internal Medicine at the Cleveland Clinic Foundation’s Akron General Medical Center the Akron Children’s Hospital. He is also a member of the faculty and research staff at Case Western University School of Medicine. Dr. Raina is a member of the University Council of Medicine at Northeast Ohio Medical University. His research interests include the pathophysiology and prevention of the progression of renal cystic disease; transition of nephrology care from pediatrics to adults; renal replacement therapy; and high flow ultrafiltration for management of inborn errors of metabolism. He has a particular interest in developing medical curricula and case-based workshops to enhance medical students’ and residents’ clinical knowledge. He has trained numerous scientists and clinical researchers from the United States and abroad, and has written several peer-reviewed articles, editorials and book chapters related to biomedical research and clinical activities. He is currently a member of the National Kidney Foundation’s Medical Advisory Board, fellow of the American College of Physicians the American Association of Pediatrics and the American Society of Nephrology, and fellow and board member of the National Kidney Foundation. 

Prof. Mignon McCulloch is currently a Pediatric Nephrologist and Consultant at the Pediatric Intensive Care Unit at the Red Cross War Memorial Children’s Hospital, Cape Town, as well as a Senior Lecturer at the University of Cape Town, South Africa. She is also an Honorary Consultant at Evelina London Children’s Hospital, United Kingdom.  

Her interests include developing pediatric nephrology and care of critically ill children, specifically acute kidney injury (AKI), and all forms of dialysis in infants and children especially in poorly resourced regions, adolescent transition and pediatric transplantation (renal, liver and cardiac). 

She is the current President Elect of the International Pediatric Transplantation Association (IPTA), Assistant Secretary of International Pediatric Nephrology Association (IPNA) and President of the African Pediatric Nephrology Association.  

She is actively involved in the ‘Saving Young Lives (SYL)’ steering committee – providing hands-on training in pediatric dialysis to teams of doctors and nurses at residential courses, including bedside PD catheter insertion, vascular access training, basic resuscitation and all forms of dialysis. 

Dr. Timothy E. Bunchman is currently tenured professor and division chief, Children’s Hospital of Richmond at Virginia Commonwealth University (VCU), USA. His primary departmental program area is pediatric nephrology. He is trained in pediatric nephrology from University of Minnesota, Minneapolis. His areas of expertise and interest are pediatric transplantation, acute kidney injury, renal replacement therapy and vasculitis. He has published papers in international journals and contributed chapters in books on pediatric nephrology and pediatric critical care. He has multiple awards to his credit and has been nominated by the American Society of Pediatric Nephrology to the National Advisory Committee on Children and Disasters (NACCD). He is on editorial board of many reputed international journals including Pediatric Critical Care Medicine, Pediatric Nephrology, and Nephrology Dialysis Transplantation. He has also been an associate editor for American Journal of Kidney Diseases. He is the organizer and program director of the International Conference on Pediatric Continuous Renal Replacement Therapy (PCRRT) endorsed by International Pediatric Nephrology Association (IPNA) as well as the critical care section of the American Academy of Pediatrics (AAP).

Bibliographic information

  • Book Title Critical Care Pediatric Nephrology and Dialysis: A Practical Handbook
  • Editors Sidharth Kumar Sethi
    Rupesh Raina
    Mignon McCulloch
    Timothy E. Bunchman
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-981-13-2275-4
  • eBook ISBN 978-981-13-2276-1
  • Edition Number 1
  • Number of Pages XIII, 378
  • Number of Illustrations 11 b/w illustrations, 37 illustrations in colour
  • Topics Nephrology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


“This handbook provides basic information about pediatric kidney diseases, renal replacement therapy, and special procedures. … This book is certainly a quick guide for pediatric nephrology and pediatric critical care postgraduate trainees as well as for pediatricians with an interest in expanding their knowledge of renal disease. The authors are true visionaries in the field.” (Aftab S. Chishti, Doody's Book Reviews, July 12, 2019)