© 2018

Proteomics of Peroxisomes

Identifying Novel Functions and Regulatory Networks

  • Luis A. del Río
  • Michael Schrader


  • Provides a comprehensive, state-of-the-art overview of proteomic analysis of peroxisomes - a field that has seen many recent developments

  • Incorporates a wealth of research on the latest proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin

  • Presents contributions from leading experts in the field


Part of the Subcellular Biochemistry book series (SCBI, volume 89)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Mass Spectrometry-Based Organelle Proteomics

    1. Front Matter
      Pages 1-1
    2. Ronghui Pan, Jianping Hu
      Pages 3-45
    3. Eden Yifrach, Sven Fischer, Silke Oeljeklaus, Maya Schuldiner, Einat Zalckvar, Bettina Warscheid
      Pages 47-66
    4. Xin Chen, Chris Williams
      Pages 67-83
    5. Markus Islinger, Andreas Manner, Alfred Völkl
      Pages 85-122
  3. Predicting Peroxisomal Proteomes

    1. Front Matter
      Pages 123-123
    2. Sigrun Reumann, Gopal Chowdhary
      Pages 125-138
    3. Johannes Freitag, Thorsten Stehlik, Alina C. Stiebler, Michael Bölker
      Pages 139-155
    4. Kristina Bersch, Ignacio Lobos Matthei, Sven Thoms
      Pages 201-219
    5. Toni Gabaldón
      Pages 221-233
    6. Matthew Anderson-Baron, Andrew J. Simmonds
      Pages 235-258
  4. Analysis of Peroxisome Proteome Interaction Networks

    1. Front Matter
      Pages 259-259
    2. Jessica Klümper, Silke Oeljeklaus, Bettina Warscheid, Ralf Erdmann, Wolfgang Schliebs
      Pages 261-285
    3. José M. Palma, Paz Álvarez de Morales, Luis A. del Río, Francisco J. Corpas
      Pages 323-341
  5. Peroxisomes in Relation to Other Subcellular Compartments

    1. Front Matter
      Pages 343-343
    2. Ronald J. A. Wanders, Hans R. Waterham, Sacha Ferdinandusse
      Pages 345-365

About this book


This new edited volume in the Springer Subcellular Biochemistry Series presents a comprehensive, state-of-the-art overview of the proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin, andcontains contributions from leading experts in the field. 

The development of sensitive proteomics and mass spectrometry technologies, combined with bioinformatics approaches now allow the identification of low-abundance and transient peroxisomal proteins and permits to identify the complete proteome of peroxisomes, with the consequent increase of our knowledge of the metabolic and regulatory networks of these important cellular organelles. The book lines-up with these developments and is organized in four sections including: (i) mass spectrometry-based organelle proteomics; (ii) prediction of peroxisomal proteomes; (iii) analysis of peroxisome proteome interaction networks; and (iv) peroxisomes in relation to other subcellular compartments.

The editor Luis A. del Río is Professor ad honorem of the Spanish National Research Council (CSIC) in the Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry and Cell & Molecular Biology of Plants, at the Estación Experimental del Zaidín, Granada, Spain. Del Río’s research group focuses on the metabolism of reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidants in plant peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in plant cell signalling. 

The editor Michael Schrader is Professor of Cell Biology & Cytopathology in the Department of Biosciences at the University of Exeter, UK. Using mammalian peroxisomes as model organelles, Prof. Schrader and his team aim to unravel the molecular machinery and signalling pathways that mediate and regulate the formation, dynamics and abundance of these medically relevant cellular compartments.


Plant Peroxisome Animal peroxisome Fungal peroxisome Drosophila peroxisome Peroxisomal proteome

Editors and affiliations

  • Luis A. del Río
    • 1
  • Michael Schrader
    • 2
  1. 1.Department of Biochemistry, Cell and Molecular Biology of PlantsEstación Experimental del Zaidín, CSICGranadaSpain
  2. 2.Department of BiosciencesUniversity of ExeterExeterUK

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