© 2018


  • Yoshiki Yamaguchi
  • Koichi Kato
  • Discusses new knowledge gained through a multidisciplinary biophysical approach

  • Describes emerging biophysical techniques in detail

  • Discusses up-to-date applications in glycobiophysics


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1104)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Yoko Amazaki, Hien Minh Nguyen, Ryo Okamoto, Yuta Maki, Yasuhiro Kajihara
    Pages 1-19
  3. Kenichi G. N. Suzuki, Hiromune Ando, Naoko Komura, Takahiro Fujiwara, Makoto Kiso, Akihiro Kusumi
    Pages 41-58
  4. Richard R. Drake, Connor A. West, Anand S. Mehta, Peggi M. Angel
    Pages 59-76
  5. Kathirvel Alagesan, Arun Everest-Dass, Daniel Kolarich
    Pages 77-99
  6. Masamichi Nagae, Yoshiki Yamaguchi
    Pages 119-147
  7. Hirokazu Yagi, Saeko Yanaka, Koichi Kato
    Pages 219-235
  8. Cristina De Castro, Garry A. Duncan, Domenico Garozzo, Antonio Molinaro, Luisa Sturiale, Michela Tonetti et al.
    Pages 237-257
  9. Back Matter
    Pages 275-277

About this book


This book presents state of the art biophysical approaches to issues in glycobiology that have cutting-edge applications. Despite the importance of glycosylation, the complexity, heterogeneity, and flexibility of the glycans have inhibited their study. Each chapter in this book explains very recent significant advances in biophysical approaches through the use of techniques such as NMR spectroscopy, mass spectrometry, single-molecule imaging, X-ray crystallography, high-speed atomic force microscopy, and computational simulation and their integrative application. Concrete examples are provided of the value of these techniques in addressing key problems in the field. In addition, significant functional glycobiological issues are considered. For example, glycolipids can form dynamic clusters on cell membranes and provide platforms for molecules involved in cell recognition and subsequent signal transduction. The detailed delineation of these molecular systems is discussed, revealing their structural complexity and ability to assemble transiently. This timely book will be of value for graduate students and postdocs interested in frontier topics in glycoscience and also for senior bio-researchers in academic and industrial fields.


Glycoscience Glycochemistry Structural Glycobiology Glycosylation Glycolipids

Editors and affiliations

  • Yoshiki Yamaguchi
    • 1
  • Koichi Kato
    • 2
  1. 1.Synthetic Cellular Chemistry LaboratoryRIKEN Cluster for Pioneering ResearchWako, SaitamaJapan
  2. 2.Exploratory Research Center on Life and Living SystemsNational Institutes of Natural SciencesOkazaki, AichiJapan

About the editors

  Yoshiki Yamaguchi, PhD

Synthetic Cellular Chemistry Laboratory

RIKEN Cluster for Pioneering Research

  Koichi Kato, PhD
Exploratory Research Center on Life and Living Systems
National Institutes of Natural Sciences

Bibliographic information

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