Zebrafish, Medaka, and Other Small Fishes

New Model Animals in Biology, Medicine, and Beyond

  • Hiromi Hirata
  • Atsuo Iida

Table of contents

  1. Front Matter
    Pages i-x
  2. Development and Cell Biology

  3. Homeostasis and Reproduction

  4. Clinical Models

    1. Front Matter
      Pages 127-127
    2. Emily Claire Baxter, Robert J. Bryson-Richardson
      Pages 151-183
    3. Long Guo, Shiro Ikegawa, Chisa Shukunami
      Pages 217-234
    4. Norihito Uemura, Ryosuke Takahashi
      Pages 235-249
  5. Eccentric Fish

About this book


This book provides cutting-edge studies and technologies using small fishes, including zebrafish, medaka, and other fishes as new model animals for molecular biology, developmental biology, and medicine. It also introduces eccentric fish models that are pioneering new frontiers of biology.

Zebrafish and medaka have been developed as lower vertebrate model organisms because these small fish are easy to raise in the laboratory and are useful for the live imaging of the morphology and activity of cells and tissues in intact animals. By virtue of those specific advantages, fish studies have demonstrated the common features of vertebrates and raised further questions toward understanding the mystery of life.

The book consists of four parts: “Development and Cell Biology”, “Homeostasis and Reproduction”, “Clinical Models”, and “Eccentric Fish”. Together they describes the core area of small fish study – often considered mere zoology but which is actually proving to be the universal basis of life.

Written by leading scientists, the book helps readers to understand small fishes, inspires scientists to utilize small fishes in their studies, and encourages anyone who wants to participate in the large and fantastic world of small fish.


Fish model Model organism Model animal Disease model Teleost fish Non-model organism Biotechnology Eccentric fish Developmental biology Vessel formation Reproduction Homeostasis Clinical model Blind fish Catfish Viviparous teleost

Editors and affiliations

  • Hiromi Hirata
    • 1
  • Atsuo Iida
    • 2
  1. 1.College of Science and EngineeringAoyama Gakuin UniversitySagamiharaJapan
  2. 2.Institute for Frontier Life and Medical SciencesKyoto UniversityKyotoJapan

Bibliographic information