© 2018

Advances in Pain Research: Mechanisms and Modulation of Chronic Pain

  • Bai-Chuang Shyu
  • Makoto Tominaga


  • Updating and outlining the most recent and outstanding of the physiology and pathology of pain

  • Covering a wide range of topics in pain research, including circuitry, neurotransmitter, neuropathology, behavior and treatments for neuropathic pain disorders

  • A valuable resource for researchers and graduate students in pain medicine and neuroscience


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1099)

Table of contents

  1. Front Matter
    Pages i-x
  2. Chen-Yu Hung, Chun-Hsiang Tan
    Pages 13-27
  3. Cheng-Han Lee, Chih-Cheng Chen
    Pages 37-47
  4. Jiro Kurata
    Pages 141-146
  5. Fusao Kato, Yae K. Sugimura, Yukari Takahashi
    Pages 157-166
  6. Zi-Fang Zhao, You Wan
    Pages 167-177
  7. Intan Low, Shyh-Yuh Wei, Pin-Shiuan Lee, Wei-Chi Li, Lin-Chien Lee, Jen-Chuen Hsieh et al.
    Pages 179-199
  8. Moe Watanabe, Minoru Narita
    Pages 201-210
  9. Yung-Hui Kuan, Hsi-Chien Shih, Bai-Chuang Shyu
    Pages 211-227

About this book


This book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for scientists to present recent findings in pain research and discuss research orientation in this field. APS 2017 focused on novel strategies for pain treatment.

Written by experts from various disciplines, from molecular to functional, and from basic to clinic studies, this book is composed of 19 review articles on the physiology and pathology of pain in these research fields. Specific topics include circuitry, neurotransmitter, physiology, behavior, neuropathology, pharmacology, and the treatments for neuropathic pain disorders. The book is a valuable resource for researchers and graduate students in pain medicine and neuroscience.


Chronic pain Nociceptive mechanisms Neuropathic pain Pain managements Pain comorbid

Editors and affiliations

  • Bai-Chuang Shyu
    • 1
  • Makoto Tominaga
    • 2
  1. 1.Division of Neuroscience, Institute of Biomedical SciencesAcademia SinicaTaipeiTaiwan
  2. 2.Division of Cell SignalingOkazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences)OkazakiJapan

About the editors

Dr. Bai Chuang Shyu is a principle investigator at the Institute of Biomedical Sciences, Academia Sinica, Taiwan. He served as the chairman of the Asian Pain Symposium, which was held in Taipei in 2017. His research focuses on the neuronal mechanisms underlying the central post stroke and information transmission in thalamocingulate circuitry in vitro. He has published more than 40 research articles in these fields.

Dr. Makoto Tominaga is a professor at the National Institutes of Physiological Sciences and National Institutes of Natural Sciences, Japan, where he leads the cell signaling division. His research focuses on regulation and function of TRP channels. Prof. Tominaga has published more than 200 articles in this field.

Bibliographic information

  • Book Title Advances in Pain Research: Mechanisms and Modulation of Chronic Pain
  • Editors Bai-Chuang Shyu
    Makoto Tominaga
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-13-1755-2
  • Softcover ISBN 978-981-13-4676-7
  • eBook ISBN 978-981-13-1756-9
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages X, 265
  • Number of Illustrations 16 b/w illustrations, 28 illustrations in colour
  • Topics Neurosciences
    Human Physiology
    Molecular Medicine
  • Buy this book on publisher's site
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