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Articular Cartilage Dynamics

  • David W. Smith
  • Bruce S. Gardiner
  • Lihai Zhang
  • Alan J. Grodzinsky

Table of contents

  1. Front Matter
    Pages i-lxiii
  2. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 1-63
  3. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 65-243
  4. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 245-309
  5. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 311-359
  6. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 361-428
  7. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 429-467
  8. David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky
    Pages 469-560
  9. Back Matter
    Pages 561-738

About this book

Introduction

This book explains the anatomy and physiology of cartilage tissue in an integrated way. The emphasis is on how cartilage tissue functions and maintains homeostasis in a challenging mechanical environment. Supported by hundreds of references, the book posts new hypotheses explaining how cartilage adapts and achieves homeostasis in vivo, and tests them against available data. This exploratory approach creates a sense of discovery that the reader can join, or perhaps test themselves through their own research. The main benefit will be obtained by research students and professors looking to understand the deeper concepts that will further their own research, or clinicians (including health professionals and surgeons) who want to gain a deeper physiological understanding of cartilage tissue, which can then serve as a basis for more rational clinical decision-making they need to make on a daily basis. To help bridge the gap between basic science and clinically relevant joint disease, applications and interpretations of key physiological concepts are discussed in the context of osteoarthritis at the end of most chapters.

Keywords

Cartilage Tissue Homeostasis Cartilage Biomechanics Joint Biolubrication Osteoarthritis Joint Disease Diarthroidal Joints Articular Cartilage Modeling Aggrecan Inflating Collagen Network Cartilage IGF System Cytokines Cartilage Degradation

Authors and affiliations

  • David W. Smith
    • 1
  • Bruce S. Gardiner
    • 2
  • Lihai Zhang
    • 3
  • Alan J. Grodzinsky
    • 4
  1. 1.Faculty of Engineering and Mathematical SciencesUniversity of Western AustraliaPerthAustralia
  2. 2.College of Science, Health, Engineering and EducationMurdoch UniversityPerthAustralia
  3. 3.Department of Infrastructure EngineeringUniversity of MelbourneMelbourneAustralia
  4. 4.Departments of Biological Engineering, Electrical Engineering, Computer Science, and Mechanical EngineeringMassachusetts Institute of TechnologyCambridgeUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-981-13-1474-2
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Engineering
  • Print ISBN 978-981-13-1473-5
  • Online ISBN 978-981-13-1474-2
  • Buy this book on publisher's site
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