Circular RNAs

Biogenesis and Functions

  • Junjie Xiao

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1087)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Rajendra Awasthi, Anurag Kumar Singh, Gaurav Mishra, Anand Maurya, Dinesh Kumar Chellappan, Gaurav Gupta et al.
      Pages 3-14
  3. Bioinformatics for Circular RNAs

    1. Front Matter
      Pages 15-15
    2. Elena López-Jiménez, Ana M. Rojas, Eduardo Andrés-León
      Pages 17-33
    3. Seyed Hamid Aghaee-Bakhtiari
      Pages 35-38
  4. Biogenesis of Circular RNAs

    1. Front Matter
      Pages 39-39
    2. Nicole Eger, Laura Schoppe, Susanne Schuster, Ulrich Laufs, Jes-Niels Boeckel
      Pages 41-52
  5. Molecular Mechanisms and Gene Regulation of Circular RNAs

    1. Front Matter
      Pages 65-65
    2. Amaresh Chandra Panda
      Pages 67-79
    3. Rumela Bose, Rupasri Ain
      Pages 81-94
    4. Shanmugapriya, Hisham Alkatib Huda, Soundararajan Vijayarathna, Chern Ein Oon, Yeng Chen, Jagat R. Kanwar et al.
      Pages 95-105
  6. Circular RNAs as Potential Disease Biomarkers

    1. Front Matter
      Pages 107-107
    2. Daniele Fanale, Simona Taverna, Antonio Russo, Viviana Bazan
      Pages 109-117
    3. Angela Vea, Vicenta Llorente-Cortes, David de Gonzalo-Calvo
      Pages 119-130
    4. Farinaz Jafari Ghods
      Pages 131-139
    5. Rupal Ojha, Raj Nandani, Nina Chatterjee, Vijay Kumar Prajapati
      Pages 141-157
    6. Qiulian Zhou, Zhongrong Zhang, Yihua Bei, Guoping Li, Tianhui Wang
      Pages 159-170
    7. Lu Xia, Meiyi Song, Mengxue Sun, Fei Wang, Changqing Yang
      Pages 171-187
  7. Circular RNAs and Human Diseases

    1. Front Matter
      Pages 189-189
    2. Lijun Wang, Xiangmin Meng, Guoping Li, Qiulian Zhou, Junjie Xiao
      Pages 191-204
    3. Lena Constantin
      Pages 205-213
    4. Susanne Lux, Lars Bullinger
      Pages 215-230
    5. S. Gokul, G. K. Rajanikant
      Pages 231-237
    6. Rumana Akhter
      Pages 239-243
    7. Meiyi Song, Lu Xia, Mengxue Sun, Changqing Yang, Fei Wang
      Pages 245-257
    8. Jianhua Yao, Qiying Dai, Zhuyuan Liu, Lei Zhou, Jiahong Xu
      Pages 259-273
    9. Tianhui Wang, Wen Pan, Jun Hu, Zhongrong Zhang, Guoping Li, Yajun Liang
      Pages 275-285
    10. Shengguang Ding, Yujiao Zhu, Yajun Liang, Haitao Huang, Yiming Xu, Chongjun Zhong
      Pages 287-297
    11. Richard Y. Cao, Qiying Dai, Qing Li, Jian Yang
      Pages 299-308
  8. Circular RNAs in Plants and in Archaea

    1. Front Matter
      Pages 327-327
    2. Xuelei Lai, Jérémie Bazin, Stuart Webb, Martin Crespi, Chloe Zubieta, Simon J. Conn
      Pages 329-343
    3. Celso Gaspar Litholdo Jr., Guilherme Cordenonsi da Fonseca
      Pages 345-353
  9. Future Prospects

    1. Front Matter
      Pages 355-355
    2. Siti Aishah Sulaiman, Nor Azian Abdul Murad, Ezanee Azlina Mohamad Hanif, Nadiah Abu, Rahman Jamal
      Pages 357-370

About this book


This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs’ biology and mechanisms of gene regulation remain unclear, they have been found to be abundant, evolutionally conserved, and stable in cells; further, they have numerous potential functions. The book consists of eight parts:1) An overview of circular RNAs, 2) Bioinformatics for circular RNAs, 3) Biogenesis of circular RNAs, 4) Molecular mechanisms and gene regulation of circular RNAs, 5) Circular RNAs as potential disease biomarkers, 6) Circular RNAs and human diseases, 7) Circular RNAs in Plants and in Archaea, and 8) Future prospects. Given its focus, the book will be especially useful for researchers and students in the fields of biochemistry, molecular biology, cell biology, and medicine.


Circular RNA Biogenesis RNA Biochemistry Human Diseases RNA binding proteins

Editors and affiliations

  • Junjie Xiao
    • 1
  1. 1.School of Life Science, Institute of Cardiovascular SciencesShanghai UniversityShanghaiChina

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-981-13-1425-4
  • Online ISBN 978-981-13-1426-1
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site
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