Functional Dyspepsia

Evidences in Pathophysiology and Treatment

  • Kazunari Tominaga
  • Hiroaki Kusunoki

Table of contents

  1. Front Matter
    Pages i-viii
  2. Etiology

    1. Front Matter
      Pages 1-1
    2. Tadayuki Oshima, Hiroto Miwa
      Pages 3-14
    3. Tomiyasu Arisawa
      Pages 15-23
    4. Hiroshi Takeda
      Pages 25-36
  3. Pathophysiology

    1. Front Matter
      Pages 37-37
    2. Kazunari Tominaga, Yoshiko Fujikawa
      Pages 39-49
    3. Yoshiko Fujikawa, Kazunari Tominaga
      Pages 51-58
    4. Hiroaki Kusunoki, Ken Haruma, Noriaki Manabe, Tomoari Kamada, Jiro Hata
      Pages 69-90
    5. Koji Yakabi, Naomi Yamaguchi, Eriko Hosomi, Toru Aoyama, Kazuhito Kani, Naoya Miyagi
      Pages 91-103
    6. Tomotaka Shoji, Yuka Endo, Shin Fukudo
      Pages 105-115
  4. Treatment

    1. Front Matter
      Pages 127-127
    2. Kouichi Sakurai, Hiroko Suda
      Pages 129-138
    3. Toshihisa Takeuchi, Satoshi Harada, Kazunari Tominaga, Kazuhide Higuchi
      Pages 139-145
    4. Yasuyuki Shimoyama, Hiroko Hosaka, Shiko Kuribayashi, Osamu Kawamura, Motoyasu Kusano
      Pages 147-152
  5. Recent Special Topics: Future Treatment Possibility

    1. Front Matter
      Pages 153-153
    2. Yuji Naito, Akifumi Fukui, Saori Kashiwagi, Tomohisa Takagi
      Pages 155-166
    3. Yoshiko Fujikawa, Kazunari Tominaga
      Pages 179-187

About this book


The research and outcomes presented in this book gather evidence concerning both the pathogenesis and treatment of functional dyspepsia. It provides the latest information on this common non-organic disease, indicating its characteristic pathogenesis based on the brain-gut interaction and micro-environment and evidence gleaned from clinical treatment. Since the pathogenesis is associated with psychology, neurology, endocrinology and bacteriology in addition to gastroenterological physiology, it is often intractable and finding a suitable treatment rationale is challenging. Furthermore, the pathogenesis varies around the world and the efficacy of treatment using standard drugs varies among different populations worldwide; accordingly, this book highlights evidence gained in clinical trials in Japan.

Functional Dyspepsia is a milestone produced by respected experts. Addressing unique topics and new findings of treatment including challenging and/or future rationales, it offers an invaluable resource for general clinicians, gastroenterologists, and basic researchers alike. 


FD Brain-Gut Interaction Motility Inflammation Acid Prokinetics Rome IV Criteria

Editors and affiliations

  • Kazunari Tominaga
    • 1
  • Hiroaki Kusunoki
    • 2
  1. 1.Premier Developmental Research of MedicineOsaka Medical CollegeTakatsukiJapan
  2. 2.Department of General MedicineKawasaki Medical SchoolKurashikiJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-981-13-1073-7
  • Online ISBN 978-981-13-1074-4
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology