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© 2018

Chromosome Translocation

  • Yu Zhang

Benefits

  • Introduces mechanisms and methodologies of chromosome translocations

  • Provides a clear overview of the basics

  • Reviews up-to-date knowledge of chromosome translocations

  • Contributions from experts in the field

Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1044)

Table of contents

  1. Front Matter
    Pages i-v
  2. Ellen S. Wilch, Cynthia C. Morton
    Pages 1-14
  3. Henrike Johanna Gothe, Vera Minneker, Vassilis Roukos
    Pages 27-38
  4. Taek-Chin Cheong, Rafael B. Blasco, Roberto Chiarle
    Pages 39-48
  5. Xiaojing Liu, Fei-Long Meng
    Pages 49-64
  6. Rajib Ghosh, Debamitra Das, Sonia Franco
    Pages 65-87
  7. Duncan M. Baird, Eric A. Hendrickson
    Pages 89-112
  8. Rachel Patton McCord, Adayabalam Balajee
    Pages 113-133
  9. Mei Chen, Yi Yang, Yu Liu, Chong Chen
    Pages 135-148

About this book

Introduction

This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases.

 

The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation.

 

It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.

Keywords

Cancer Chromosome Translocation DNA repair Genome Organization Next Generation Sequencing

Editors and affiliations

  • Yu Zhang
    • 1
  1. 1.National Institute of Biological SciencesBeijingChina

About the editors

Dr. Yu Zhang is Assistant Investigator at National Institute of Biological Sciences, Beijing, China.

Bibliographic information

  • Book Title Chromosome Translocation
  • Editors Yu Zhang
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI https://doi.org/10.1007/978-981-13-0593-1
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-13-0592-4
  • Softcover ISBN 978-981-13-4459-6
  • eBook ISBN 978-981-13-0593-1
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages V, 168
  • Number of Illustrations 2 b/w illustrations, 27 illustrations in colour
  • Topics Human Genetics
    Cell Biology
  • Buy this book on publisher's site
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