© 2018

Drosophila Models for Human Diseases

  • Masamitsu Yamaguchi


  • Discusses specific and commonly used techniques involving the Drosophila model

  • Provides not only reviews but also protocols commonly used in laboratories related to each subject

  • Equips designers to develop a screening kit for new medicines using the Drosophila model


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1076)

Table of contents

  1. Front Matter
    Pages i-x
  2. Masamitsu Yamaguchi, Hideki Yoshida
    Pages 1-10
  3. Koji Takeda, Takashi Okumura, Kiichiro Taniguchi, Takashi Adachi-Yamada
    Pages 11-23
  4. Leo Tsuda, Young-Mi Lim
    Pages 25-40
  5. Vuu My Dung, Dang Thi Phuong Thao
    Pages 41-61
  6. Morio Ueyama, Yoshitaka Nagai
    Pages 63-78
  7. Yumiko Azuma, Ikuko Mizuta, Takahiko Tokuda, Toshiki Mizuno
    Pages 79-95
  8. Masamitsu Yamaguchi, Hiroshi Takashima
    Pages 97-117
  9. Saranyapin Potikanond, Wutigri Nimlamool, Jasprien Noordermeer, Lee G. Fradkin
    Pages 147-172
  10. Masato Enomoto, Carmen Siow, Tatsushi Igaki
    Pages 173-194
  11. Manon Boulet, Marion Miller, Laurence Vandel, Lucas Waltzer
    Pages 195-214
  12. Yoshihiro H. Inoue, Hiroka Katsube, Yukiko Hinami
    Pages 235-256
  13. Toshiyuki Takano-Shimizu-Kouno, Takashi Ohsako
    Pages 277-288
  14. Julia Cassim, Frank Kolkman, Marcel Helmer
    Pages 289-305
  15. Back Matter
    Pages 307-308

About this book


Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila’s value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases.

The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases. 


Gene function Drug screen Metabolomics Neurology Animal model

Editors and affiliations

  • Masamitsu Yamaguchi
    • 1
  1. 1.Department of Applied BiologyKyoto Institute of TechnologyKyotoJapan

About the editors

Masamitsu Yamaguchi received his PhD from Osaka University and is currently a Professor of Applied Biology, Kyoto Institute of Technology. He is a former director of the Advanced Insect Research Promotion Center at Kyoto Institute of Technology. 

Bibliographic information

Industry Sectors
Health & Hospitals