© 2018

The Hair Fibre: Proteins, Structure and Development

  • Jeffrey E. Plowman
  • Duane P. Harland
  • Santanu Deb-Choudhury
  • Is the first book that brings together decades of research on keratin biochemistry and fibre

  • Fills a gap in the market for a research book in the scientific, cosmetic and medical areas

  • Has contributions from globally recognized experts in their field


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1054)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Introduction to Hair and Follicles

    1. Front Matter
      Pages 1-1
    2. Jeffrey E. Plowman, Duane P. Harland
      Pages 3-13
    3. Jeffrey E. Plowman, Duane P. Harland
      Pages 15-17
  3. Hair Proteins

    1. Front Matter
      Pages 19-19
    2. Leopold Eckhart, Florian Ehrlich
      Pages 33-45
    3. Dong-Dong Wu, David M. Irwin
      Pages 47-56
    4. R. D. Bruce Fraser, David A. D. Parry
      Pages 57-70
    5. R. D. Bruce Fraser, David A. D. Parry
      Pages 71-86
  4. Hair Development

    1. Front Matter
      Pages 87-87
    2. Duane P. Harland
      Pages 89-96
    3. Duane P. Harland
      Pages 97-108
    4. Duane P. Harland, Jeffrey E. Plowman
      Pages 109-154
    5. Duane P. Harland, A. John McKinnon
      Pages 155-169
  5. Hair Chemistry and Thermodynamics

    1. Front Matter
      Pages 171-171
    2. Crisan Popescu
      Pages 185-203
    3. Jolon M. Dyer
      Pages 205-218
  6. Back Matter
    Pages 219-225

About this book


Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form.

To achieve this the book has been divided into three sections.  The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre.

The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins.

This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.


Keratin Structure Keratin Assembly Keratin associated proteins Intermediate filament architecture Modification of keratins

Editors and affiliations

  • Jeffrey E. Plowman
    • 1
  • Duane P. Harland
    • 2
  • Santanu Deb-Choudhury
    • 3
  1. 1.AgResearch Ltd.LincolnNew Zealand
  2. 2.AgResearch Ltd.LincolnNew Zealand
  3. 3.AgResearch Ltd.LincolnNew Zealand

Bibliographic information

  • Book Title The Hair Fibre: Proteins, Structure and Development
  • Editors Jeffrey E. Plowman
    Duane P. Harland
    Santanu Deb-Choudhury
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-10-8194-1
  • Softcover ISBN 978-981-13-4089-5
  • eBook ISBN 978-981-10-8195-8
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages VIII, 225
  • Number of Illustrations 34 b/w illustrations, 42 illustrations in colour
  • Topics Human Physiology
  • Buy this book on publisher's site
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