Zic family

Evolution, Development and Disease

  • Jun Aruga

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1046)

Table of contents

  1. Front Matter
    Pages i-x
  2. Zic Family in Animal Evolution and Development

    1. Front Matter
      Pages 1-1
    2. Jun Aruga, Minoru Hatayama
      Pages 3-26
    3. Michael J. Layden
      Pages 27-39
    4. Deborah A. Hursh, Brian G. Stultz
      Pages 41-58
    5. Jun Aruga
      Pages 69-86
    6. Yutaka Satou, Kaoru S. Imai
      Pages 87-106
    7. Christa Merzdorf, Jennifer Forecki
      Pages 107-140
    8. Kota Abe, Toru Kawanishi, Hiroyuki Takeda
      Pages 141-156
    9. Cecilia Lanny Winata, Vladimir Korzh
      Pages 157-177
    10. Koula E. M. Diamand, Kristen S. Barratt, Ruth M. Arkell
      Pages 179-207
    11. Eloísa Herrera
      Pages 209-230
  3. Zic Family in Medicine

    1. Front Matter
      Pages 231-231
    2. Kristen S. Barratt, Ruth M. Arkell
      Pages 269-299
    3. Helen M. Bellchambers, Stephanie M. Ware
      Pages 301-327
    4. Rob Houtmeyers, Jabob Souopgui, Sabine Tejpar
      Pages 329-338

About this book


This book provides a comprehensive overview of ZIC-family research. Part1 summarizes the ZIC family in animal evolution and development and presents an overall picture of the ZIC family gene structure in eumetazoan animals, providing an evolutionary hypothesis and reviewing the studies on the role of ZIC family proteins in developmental processes for each animal model. Part 2 shows that the ZIC family are the causative genes for developmental disorders, and discusses the role of the ZIC family in stem cell biology. It also presents studies on the ZIC family in the medical biology field. This interdisciplinary book is a valuable resource not only for those people directly involved in ZIC-family-related research, but also researchers in diverse research fields who are interested in the latest advances in biology and medicine.   


Evolution of the nervous system Stem cell biology Genetic basis of congenital anomalies Cancer biology Animal development Animal body plan

Editors and affiliations

  • Jun Aruga
    • 1
  1. 1.Graduate School of Biomedical SciencesNagasaki UniversityNagasakiJapan

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