© 2017

Substance and Non-substance Addiction

  • Xiaochu Zhang
  • Jie Shi
  • Ran Tao

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1010)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Overview of Substance and Non-substance Addictions

    1. Front Matter
      Pages 1-1
    2. Yamikani Ndasauka, Zhengde Wei, Xiaochu Zhang
      Pages 3-19
    3. Zhiling Zou, Huijun Wang, Federico d’Oleire Uquillas, Xiaomei Wang, Jianrui Ding, Hong Chen
      Pages 21-41
  3. Comparison Between Substance and Non-substance Addictions in Mechanism

    1. Front Matter
      Pages 43-43
    2. Manli Chen, Yan Sun, Lin Lu, Jie Shi
      Pages 45-58
    3. Yang Zhang, Yan Sun, Jie Liang, Lin Lu, Jie Shi
      Pages 59-71
    4. Yan-Kun Sun, Yan Sun, Xiao Lin, Lin Lu, Jie Shi
      Pages 73-89
    5. Yu Chen, Yan Sun, Si-Zhi Ai, Jason J. Li, Lin Lu, Jie Shi
      Pages 91-101
  4. Comparison Between Substance and Non-substance Addictions in Diagnosis

    1. Front Matter
      Pages 103-103
    2. Zhengde Wei, Xiaochu Zhang
      Pages 105-132
    3. Bin Xuan, Peng Li, Liping Yang, Mingzhu Li, Jing Zhou
      Pages 133-168
    4. Wenwen Shen, Huifeng Liu, Xiaohu Xie, Haixiong Liu, Wenhua Zhou
      Pages 169-202
  5. Comparison Between Substance and Non-substance Addictions in Treatment

    1. Front Matter
      Pages 217-217
    2. Ri-Hui He, Ran Tao
      Pages 219-245
    3. Li-Jun Xiao, Ran Tao
      Pages 247-260
    4. Li-Jun Xiao, Ran Tao
      Pages 261-280
    5. Li-Jun Xiao, Ran Tao
      Pages 281-293
    6. Ri-Hui He, Ran Tao
      Pages 295-320

About this book


This book focuses on the similarities and differences between substance and non-substance addictions. It discusses in detail the mechanisms, diagnosis and treatment of substance and non-substance addictions, and addresses selected prospects that will shape future studies on addiction. Addiction is a global problem that costs millions of lives tremendous damage year after year. There are mainly two types of addition: substance addiction (e.g., nicotine, alcohol, cannabis, heroin, stimulants, etc.) and non-substance addiction (e.g., gambling, computer gaming, Internet, etc.). Based on existing evidence, both types of addiction produce negative impacts on individuals’ physical, mental, social and financial well-being, and share certain common mechanisms, which involve a dysfunction of the neural reward system and specific gene transcription factors. However, there are also key differences between these two types of addiction. Covering these aspects systematically, the book will provide researchers and graduate students alike a better understanding of drug and behavioral addictions.


Substance Addiction Non-substance Addictionf Neural mechanisms Diagnosis Clinic therapy

Editors and affiliations

  • Xiaochu Zhang
    • 1
  • Jie Shi
    • 2
  • Ran Tao
    • 3
  1. 1.Key Laboratory of Brain Function and Disease, Chinese Academy of Sciences, and School of Life SciencesUniversity of Science & Technology of ChinaHefeiChina
  2. 2.National Institute on Drug DependencePeking UniversityBeijingChina
  3. 3.Department of Psychological MedicinePLA Army General HospitalBeijingChina

About the editors

Dr. Xiaochu Zhang is a professor at the School of Life Sciences, University of Science and Technology of China, and a principal investigator at the Cognitive Neuropsychology Lab. His research focuses on the neural basis of drug and behavior addiction and its applications to addiction treatment. He has published more than 30 articles in international peer-reviewed journals.

Dr. Jie Shi is a principal investigator and Associate Director of the National Institute on Drug Dependence, Peking University. She is also vice chairwoman of the Drug Dependence Branch of the Chinese Society for Toxicology (CST) and a committee member of the physiopsychology branch of the Chinese Psychological Society. Her research focuses on neural imaging of patients with drug addiction and clinical pharmacology. Dr. Shi has published more than 40 research articles in these fields.

Dr. Ran Tao is a chief physician and director of the Internet Addiction Treatment Center, General Hospital of Beijing Military Region. He is also chairman of the Beijing Shijian Integrated Medicine Science Institute and director of the Adolescent Psychological Development Base in China. His research focuses on addiction biology, especially Internet addiction, and he has published several articles in this field.    

Bibliographic information

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