© 2018

Hepatitis B Virus and Liver Disease

  • Jia-Horng Kao
  • Ding-Shinn Chen
  • Provides a comprehensive summary of the advances in patient management to stimulate further research

  • Discusses the latest clinical and scientific information

  • Serves as a valuable resource for medical students, physicians and researchers dealing with, and interested in, this challenging viral infection


Table of contents

  1. Front Matter
    Pages i-xvii
  2. Darren J. Wong, Stephen A. Locarnini
    Pages 1-23
  3. Kazuaki Chayama, C. Nelson Hayes
    Pages 25-43
  4. Fu-Sheng Wang, Ji-Jing Shi
    Pages 45-62
  5. Yael Bogler, Robert J. Wong, Robert G. Gish
    Pages 63-89
  6. John W. Ward, Pierre Van Damme
    Pages 91-117
  7. Hung-Chih Yang
    Pages 119-133
  8. Masaya Sugiyama, Tadasu Shin-I, Masashi Mizokami
    Pages 135-142
  9. Valerie Fako, Xin W. Wang
    Pages 143-162
  10. Henry Lik-Yuen Chan, Vincent Wai-Sun Wong
    Pages 163-179
  11. Tarik Asselah, Patrick Marcellin
    Pages 181-191
  12. Jonggi Choi, Young-Suk Lim
    Pages 193-217
  13. Di Wu, Qin Ning
    Pages 219-237
  14. Carla S. Coffin, Norah A. Terrault
    Pages 239-262
  15. Ming-Wei Lai, Huey-Ling Chen, Mei-Hwei Chang
    Pages 263-296
  16. Man-Fung Yuen
    Pages 297-313
  17. Jau-Hau Horng, Chang-Ru Wu, Pei-Jer Chen
    Pages 343-353
  18. Back Matter
    Pages 355-360

About this book


This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in management of patients with chronic HBV infection and investigation HBV infection.


hepatocellular carcinoma hepatitis B virus HBV chronic hepatitis liver cirrhosis immunosuppressive therapy Immunopathogenesis hepatology infectious diseases

Editors and affiliations

  • Jia-Horng Kao
    • 1
  • Ding-Shinn Chen
    • 2
  1. 1.Graduate Institute of Clinical MedicineNational Taiwan University College of MedicineTaipeiTaiwan
  2. 2.Graduate Institute of Clinical MedicineNational Taiwan University College of Medicine, Genomics Research CenterAcademia SinicaTaipeiTaiwan

About the editors

Editor Jia-Horng Kao is a Professor at the Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan. Professor Ding-Shinn Chen is a Professor at the Genomics Research Center, and the Academician of Academic Sinica, Taipei, Taiwan.

Bibliographic information

  • Book Title Hepatitis B Virus and Liver Disease
  • Editors Jia-Horng Kao
    Ding-Shinn Chen
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-981-10-4842-5
  • Softcover ISBN 978-981-13-5245-4
  • eBook ISBN 978-981-10-4843-2
  • Edition Number 1
  • Number of Pages XVII, 360
  • Number of Illustrations 11 b/w illustrations, 29 illustrations in colour
  • Topics Hepatology
    Infectious Diseases
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


“The purpose is to present updated information regarding the pathogenesis, epidemiology, and prevention of hepatitis B, with a strong emphasis on basic and translational medicine. The audience includes students, healthcare providers, and researchers interested in hepatitis B or who wish to stay up to date in this area. The book would be of the greatest benefit to research‐oriented readers and/or those working in geographic areas highly endemic in hepatitis B.” (Cezarina Mindru, Doody's Book Reviews, April, 2018)