© 2017

Exosomes in Cardiovascular Diseases

Biomarkers, Pathological and Therapeutic Effects

  • Junjie Xiao
  • Sanda Cretoiu
  • Provides the first intensive overview on exosomes in cardiovascular diseases

  • Covers future prospects of the research

  • Contributed by leading experts in the field


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 998)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Claudia Arenaccio, Maurizio Federico
      Pages 3-19
  3. Basic Aspects of Exosomes

    1. Front Matter
      Pages 21-21
    2. Alice Conigliaro, Simona Fontana, Stefania Raimondo, Riccardo Alessandro
      Pages 23-43
    3. Maarten Vanhaverbeke, Diane Gal, Paul Holvoet
      Pages 45-58
  4. Exosomes as Biomarkers of Cardiovascular Diseases

    1. Front Matter
      Pages 59-59
    2. Yihua Bei, Pujiao Yu, Dragos Cretoiu, Sanda Maria Cretoiu, Junjie Xiao
      Pages 71-88
  5. Pathological Effects of Exosomes

    1. Front Matter
      Pages 89-89
    2. Valter Vinícius Silva Monteiro, Jordano Ferreira Reis, Rafaelli de Souza Gomes, Kely Campos Navegantes, Marta Chagas Monteiro
      Pages 101-112
    3. Esam S. B. Salem, Guo-Chang Fan
      Pages 113-138
    4. Huanyu Gu, Qiying Dai, Zhuyuan Liu, Hongbao Wang, Jianhua Yao, Lei Zhou
      Pages 139-149
    5. Marcel Liberman, Luciana Cavalheiro Marti
      Pages 151-160
  6. Therapeutic Effects of Exosomes

    1. Front Matter
      Pages 161-161
    2. Shengguang Ding, Jingying Zhang, Qiying Dai, Mengfei Zhao, Haitao Huang, Yiming Xu et al.
      Pages 163-177
    3. Etsu Suzuki, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu
      Pages 179-185
    4. Yao-Hua Song, Lianbo Shao, Yu Zhang, Jin Zhou, Bin Liu, Xiangbin Pan et al.
      Pages 187-206
    5. E. A. Mol, M. J. Goumans, J. P. G. Sluijter
      Pages 207-219

About this book


The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. It firstly describes the general aspects of exosomes including the definition, formation and secretion of exosomes and highlight their roles as biomarkers and pathological and therapeutic effects in cardiovascular diseases as well. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized. Thirdly, exosomes as biomarkers of cardiovascular diseases are overviewed including their roles in diagnosis, prognosis and reaction to therapy. Fourthly, pathological effects of exosomes and therapeutic effects of exosomes are highlighted. Finally, future prospects of exosomes in cardiovascular research would be provided. This is an essential reference for researchers working in cell biology and regeneration, as well as clinicians such as cardiologist.


Cardiovascular diseases exosomes cardiovascular exosomes biomarkers of cardiovascular diseases Therapeutic Effects Pathological effects

Editors and affiliations

  • Junjie Xiao
    • 1
  • Sanda Cretoiu
    • 2
  1. 1.Shanghai University ShanghaiChina
  2. 2.Victor Babeş National Institute of Patho BucharestRomania

About the editors

Dr. Junjie Xiao is Principal Investigator and Associate Professor at Cardiac Regeneration and Ageing Lab in Shanghai University, Shanghai, China;

Dr. Sanda Cretoiu is an Associate Professor at Victor Babeş National Institute of Pathology, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.

Bibliographic information

  • Book Title Exosomes in Cardiovascular Diseases
  • Book Subtitle Biomarkers, Pathological and Therapeutic Effects
  • Editors Junjie Xiao
    Sanda Cretoiu
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2017
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-10-4396-3
  • Softcover ISBN 978-981-13-5127-3
  • eBook ISBN 978-981-10-4397-0
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages VII, 307
  • Number of Illustrations 2 b/w illustrations, 30 illustrations in colour
  • Topics Molecular Medicine
    Human Physiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals