© 2017

Exercise for Cardiovascular Disease Prevention and Treatment

From Molecular to Clinical, Part 2

  • Junjie Xiao
  • Summarizes the acute and chronic response to exercise

  • Covers a wide range of biomedical research areas

  • Provides future prospects of the research


Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1000)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Exercise Benefits the Heart: Clinical Evidence

    1. Front Matter
      Pages 1-1
    2. Lei Wang, Dongmei Ai, Ning Zhang
      Pages 3-7
    3. Zhuyuan Liu, Huanyu Gu, Qiying Dai, Hongbao Wang, Jianhua Yao, Lei Zhou
      Pages 9-29
    4. Ivana C. Moraes-Silva, Cristiano Teixeira Mostarda, Antonio Carlos Silva-Filho, Maria Claudia Irigoyen
      Pages 65-84
    5. Caterina Lambiase, Silvia Macerola, Giovanna Bosco, Elisa Messina, Pasquale Franciosa
      Pages 85-93
    6. Junnan Wang, Bin Liu
      Pages 95-101
    7. Elena Cavarretta, Giorgio Mastroiacovo, Annik Lupieri, Giacomo Frati, Mariangela Peruzzi
      Pages 103-129
    8. Peipei Han, Wen Zhang, Li Kang, Yixuan Ma, Liyuan Fu, Liye Jia et al.
      Pages 131-151
    9. Abraham Samuel Babu, Ross Arena, Norman R. Morris
      Pages 153-172
  3. Molecular Mechanisms

    1. Front Matter
      Pages 185-185
    2. Kate L. Weeks, Bianca C. Bernardo, Jenny Y. Y. Ooi, Natalie L. Patterson, Julie R. McMullen
      Pages 187-210
    3. Tiago Fernandes, Camila V. Gomes-Gatto, Noemy P. Pereira, Yahya R. Alayafi, Vander J. das Neves, Edilamar M. Oliveira
      Pages 211-245
    4. Shengguang Ding, Tianyi Gan, Meiyi Song, Qiying Dai, Haitao Huang, Yiming Xu et al.
      Pages 247-259
    5. Yihua Bei, Lichan Tao, Dragos Cretoiu, Sanda Maria Cretoiu, Junjie Xiao
      Pages 261-280
    6. Ursula Paula Renó Soci, Stephano Freitas Soares Melo, João Lucas Penteado Gomes, André Casanova Silveira, Clara Nóbrega, Edilamar Menezes de Oliveira
      Pages 281-322

About this book


The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc.


Beneficial effects of exercise in cardiac Cardiovascular diseases Cardiac Exercise Physiology Cardiac Cells Adaptations Cardiac aging Coronary heart disease

Editors and affiliations

  • Junjie Xiao
    • 1
  1. 1.Cardiac Regeneration and Ageing Lab, School of Life ScienceShanghai UniversityShanghaiChina

About the editors

Dr. Junjie Xiao is Principal Investigator and Associate Professor at Regeneration and Ageing Lab in Shanghai University, Shanghai, China

Bibliographic information

  • Book Title Exercise for Cardiovascular Disease Prevention and Treatment
  • Book Subtitle From Molecular to Clinical, Part 2
  • Editors Junjie Xiao
  • Series Title Advances in Experimental Medicine and Biology
  • Series Abbreviated Title Adv Exp Med Biol
  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2017
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-981-10-4303-1
  • Softcover ISBN 978-981-13-5100-6
  • eBook ISBN 978-981-10-4304-8
  • Series ISSN 0065-2598
  • Series E-ISSN 2214-8019
  • Edition Number 1
  • Number of Pages VII, 387
  • Number of Illustrations 6 b/w illustrations, 33 illustrations in colour
  • Topics Human Physiology
    Molecular Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals