Decision Making in a World of Comparative Effectiveness Research

A Practical Guide

  • Howard G. Birnbaum
  • Paul E. Greenberg

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Dave Nellesen, Howard G. Birnbaum, Paul E. Greenberg
      Pages 5-14
  3. The Future of Comparative Effectiveness Research for Evidence Developers: Perspectives from Pharmaceutical Decision Makers

  4. Evolving Stakeholder Considerations: Patients, Physicians, Regulators and Payers

    1. Front Matter
      Pages 95-95
    2. Louis F. Rossiter
      Pages 117-136
    3. Anna Hung, Carole Baas, Justin Bekelman, Marcy Fitz-Randolph, C. Daniel Mullins
      Pages 137-152
    4. Jipan Xie, Kalipso Chalkidou, Isao Kamae, Rebecca E. Dittrich, Rifaiyat Mahbub, Arjun Vasan et al.
      Pages 153-166
    5. Patrick Lefebvre, Marie-Hélène Lafeuille, Sean Tiggelaar
      Pages 167-179
    6. Patrick Lefebvre, Marie-Hélène Lafeuille, Sean Tiggelaar
      Pages 181-189
    7. Paul Kalb, Paul E. Greenberg, Crystal T. Pike
      Pages 209-217
  5. Emerging Challenges, Methods and Applications of Comparative Effectiveness Research: Real-World and Big Data

    1. Front Matter
      Pages 219-219
    2. Eberechukwu Onukwugha, Rahul Jain, Husam Albarmawi
      Pages 253-263
    3. James Signorovitch, Jie Zhang
      Pages 265-276
    4. Nick Dadson, Lisa Pinheiro, Jimmy Royer
      Pages 277-289

About this book


In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have edited a book that provides a practical guide to decision making using the results of analysis and interpretation of CER. Decision Making in a World of Comparative Effectiveness contains chapters by senior industry executives, key opinion leaders, accomplished researchers, and leading attorneys involved in resolving disputes in the life sciences industry. The book is aimed at 'users' and 'decision makers' involved in the life sciences industry rather than those doing the actual research. This book appeals to those who commission CER within the life sciences industry (pharmaceutical, biologic, and device manufactures), government (both public and private payers), as well as decision makers of all levels, both in the US and globally. 


Big Data Comparative Effectiveness Health Economics Health Policy Health Technology Assessment Pharmacoeconomics

Editors and affiliations

  • Howard G. Birnbaum
    • 1
  • Paul E. Greenberg
    • 2
  1. 1.Analysis Group, Inc.BostonUSA
  2. 2.Analysis Group, Inc.BostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2017
  • Publisher Name Adis, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-10-3261-5
  • Online ISBN 978-981-10-3262-2
  • Buy this book on publisher's site
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