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© 2016

Biophotonics

Concepts to Applications

  • Introduces senior-level and postgraduate students to the principles and applications of biophotonics

  • Serves as a valuable reference resource for practicing physicians, clinicians, biomedical researchers, and biomedical engineers working with photonics-based tools and instruments

  • Includes worked examples and drill problems throughout

  • Written by an expert in the field of optics and biophotonics

Textbook

Part of the Graduate Texts in Physics book series (GTP)

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Gerd Keiser
    Pages 1-23
  3. Gerd Keiser
    Pages 25-51
  4. Gerd Keiser
    Pages 91-118
  5. Gerd Keiser
    Pages 119-146
  6. Gerd Keiser
    Pages 147-196
  7. Gerd Keiser
    Pages 197-232
  8. Gerd Keiser
    Pages 233-258
  9. Gerd Keiser
    Pages 259-290
  10. Gerd Keiser
    Pages 291-321
  11. Gerd Keiser
    Pages 323-337
  12. Gerd Keiser
    Pages E1-E2
  13. Back Matter
    Pages 339-345

About this book

Introduction

This book is designed to introduce senior-level and postgraduate students to the principles and applications of biophotonics. It also will serve well as a working reference to practicing physicians, clinicians, biomedical researchers, and biomedical engineers dealing with photonics-based tools and instruments. The book topics include the fundamentals of optics and photonics, the optical properties of biological tissues, various types of light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of healthy and diseased tissue, and optical biomedical imaging. The tools and techniques described in the book include laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, nanophotonics, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), flow cytometery, photodynamic therapy (PDT), low-level light therapy (LLLT), tissue characterization, and laser ablation. To assist readers in learning the material and applying it to practical designs, the book will include worked out examples and drill problems throughout. A collection of homework problems is included to help test the reader’s comprehension of the material covered, and to extend and elucidate the text.This book introduces senior-level and postgraduate students to the principles and applications of biophotonics. It also serves as a valuable reference resource or as a short-course textbook for practicing physicians, clinicians, biomedical researchers, healthcare professionals, and biomedical engineers and technicians dealing with the design, development, and application of photonics components and instrumentation to biophotonics issues. The topics include the fundamentals of optics and photonics, the optical properties of biological tissues, light-tissue interactions, microscopy for visualizing tissue components, spectroscopy for optically analyzing the properties of tissue, and optical biomedical imaging. It also describes tools and techniques such as laser and LED optical sources, photodetectors, optical fibers, bioluminescent probes for labeling cells, optical-based biosensors, surface plasmon resonance, and lab-on-a-chip technologies. Among the applications are optical coherence tomography (OCT), optical imaging modalities, photodynamic therapy (PDT), photobiostimulation or low-level light therapy (LLLT), diverse microscopic and spectroscopic techniques, tissue characterization, laser tissue ablation, optical trapping, and optogenetics. Worked examples further explain the material and how it can be applied to practical designs, and the homework problems help test readers’ understanding of the text.

Keywords

Lab-on-a-Chip Biophotonics Biophotonics Textbook Biosensors Fluorescence Optical Imaging Spectroscopy Light-Tissue Interactions Microscopy Optical Trapping

Authors and affiliations

  1. 1.Department of Electrical and Computer EngineeringBoston UniversityNewtonUSA

About the authors

After obtaining his doctorate in physics from Northeastern University, Dr. Gerd Keiser worked in the telecommunications industry at Honeywell, GTE, General Dynamics, and PhotonicsComm Solutions, where his work involved research and application of optical networking technology and digital switch implementations for telecom systems. While he was at GTE, he was the recipient of the prestigious Leslie Warner Award from GTE for ATM switch development. During this time he also was an Adjunct Professor of electrical engineering at Northeastern University, Tufts University, and Boston University. Since 2007, he has been with the National Taiwan University of Science and Technology in Taipei, Taiwan. He is a Fellow of the IEEE, a member of OSA and SPIE, and an Associate Editor of the journal Optical Fiber Technology. He has given numerous invited talks, papers, short courses, and keynote speeches at international conferences. In addition, he is the author of four graduate-level books: Optical Fiber Communications, Local Area Networks, Optical Communication Essentials, and FTTX Concepts and Applications. His professional experience and research interests are in the general areas of optical networking technology and biophotonics.

Bibliographic information

Industry Sectors
Pharma

Reviews

“Biophotomcs is a good textbook and will undoubtedly be a valuable lecture Supplement in an advanced undergraduate or graduate-level course. … the material is pertinent and is presented clearly enough to provide a springboard for further study” (Arjun Yodh, Physics Today, February, 2018)