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© 2015

Advance in Structural Bioinformatics

  • Dongqing Wei
  • Qin Xu
  • Tangzhen Zhao
  • Hao Dai

Benefits

  • Presents the core algorithms and mathematical models for sequence analysis

  • Provides systematic and detailed methodologies and application

  • Includes the most recent progress in the field

Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 827)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Qin Xu, Hao Dai, Tangzhen Zhao, Dongqing Wei
    Pages 1-7
  3. Advances in Methods for Structural Bioinformatics

    1. Front Matter
      Pages 9-9
    2. Peijun Xu, Jinguang Wang, Yong Xu, Huiying Chu, Jiahui Liu, Meixia Zhao et al.
      Pages 19-32
    3. Yukun Wang, Ruoxu Gu, Huaimeng Fan, Jakob Ulmschneider, Dongqing Wei
      Pages 71-82
  4. 3D-Structure Prediction and Folding Mechanism of Biological Macromolecules

    1. Front Matter
      Pages 83-83
    2. Lei Wei, Ping Jiang, Malathy Sony Subramanian Manimekalai, Cornelia Hunke, Gerhard Grüber, Konstantin Pervushin et al.
      Pages 85-92
    3. Xue Wu, Peijun Xu, Jinguang Wang, Yong Xu, Ting Fu, Depeng Zhang et al.
      Pages 93-110
    4. Xue Wu, Peijun Xu, Jinguang Wang, Yong Xu, Ting Fu, Meixia Zhao et al.
      Pages 123-141
    5. Zhijie Tan, Wenbing Zhang, Yazhou Shi, Fenghua Wang
      Pages 143-183
  5. The Interactions Between Biological Macromolecules and Ligands

    1. Front Matter
      Pages 185-185
    2. Peijun Xu, Jinguang Wang, Yong Xu, Huiying Chu, Hujun Shen, Depeng Zhang et al.
      Pages 187-203
    3. Ruoxu Gu, Limin Angela Liu, Dongqing Wei
      Pages 205-226
  6. Functional Analysis of Biological Macromolecules

    1. Front Matter
      Pages 259-259
    2. Zhao Zhang, Ze Wang, Guoqin Mai, Youxi Luo, Miaomiao Zhao, Fengfeng Zhou
      Pages 261-274

About this book

Introduction

This text examines in detail mathematical and physical modeling, computational methods and systems for obtaining and analyzing biological structures, using pioneering research cases as examples. As such, it emphasizes programming and problem-solving skills. It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, from fundamental methods and guidelines on acquiring and analyzing genomics and proteomics sequences, the structures of protein, DNA and RNA, to the basics of physical simulations and methods for conformation searches.
This book will be of immense value to researchers and students in the fields of bioinformatics, computational biology and chemistry.
Dr. Dongqing Wei is a Professor at the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. His research interest is in the general area of structural bioinformatics.

Keywords

Biological Macromolecules Molecular Modeling Structural Predictions Structural bioinformatics

Editors and affiliations

  • Dongqing Wei
    • 1
  • Qin Xu
    • 2
  • Tangzhen Zhao
    • 3
  • Hao Dai
    • 4
  1. 1.Shanghai JiaoTong UniversityShanghaiChina
  2. 2.Shanghai Jiao Tong UniversityShanghaiChina
  3. 3.Shanghai Jiao Tong UniversityShanghaiChina
  4. 4.Shanghai Jiao Tong UniversityShanghaiChina

About the editors

Dr. Dongqing Wei is professor at the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiaotong University, China. He serves as Editor-in-Chief for journal of Interdisciplinary Sciences-Computational Life Sciences. He is chairman of International Association of Scientists in the Interdisciplinary Areas (IASIA). Prof. Wei’s research is in the general area of structural bioinformatics. He has made many important contributions to sciences. With more than 150 journal papers and SCI 3000 citations, he is becoming a leading figure in the area of structural bioinformatics. Prof. Wei organized a few important international conferences recently, for example, International Conference on Computational and System Biology, 2009-2011, Shanghai, China; Theory and Application of Computational Chemistry, Sept. 23-27, 2008, Shanghai, China; 2nd IEEE Conferences on Bioinformatics and Biomedical Engineering, May 16-20, 2008, Shanghai, China.

Bibliographic information

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