© 2016

Principles of Cancer Genetics


Table of contents

  1. Front Matter
    Pages i-xii
  2. Fred Bunz
    Pages 1-46
  3. Fred Bunz
    Pages 47-74
  4. Fred Bunz
    Pages 75-134
  5. Fred Bunz
    Pages 135-186
  6. Fred Bunz
    Pages 187-201
  7. Fred Bunz
    Pages 203-270
  8. Fred Bunz
    Pages 271-303
  9. Fred Bunz
    Pages 305-336
  10. Back Matter
    Pages 337-343

About this book


This is the second edition of a widely used  textbook that consolidates the basic concepts of the cancer gene theory and provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in genetics, biology and biochemistry, medical students and medical house staff.  For students with a general interest in cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future study in the field of oncology and cancer research, this concise book will be useful as a primer.


Cancer Oncogenes Tumor suppressor genes Genetic Instability Genetics

Authors and affiliations

  1. 1.The Johns Hopkins UniversityBaltimoreUSA

About the authors

Fred Bunz, M.D., Ph.D is a native of Long Beach, New York. He attended Stony Brook University and graduated from its Medical Scientist Training Program. His doctoral research in the enzymology of human DNA replication was conducted at Cold Spring Harbor Laboratory. Dr. Bunz completed a postdoctoral fellowship in Cancer Genetics at The Johns Hopkins University and the Howard Hughes Medical Institute, and now heads a laboratory at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins that is focused on understanding the effects of DNA damage on cancer cells and normal cells. He lives in Baltimore with his wife, two children, a cat, and an Old English Sheepdog. 

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods