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Organ Preservation

Basic and Applied Aspects A Symposium of the Transplantation Society

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  • © 1982
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Overview

Editors:
  1. D. E. Pegg

    1. MRC Medical Cryobiology Group, University Department of Surgery, Cambridge, UK

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  2. I. A. Jacobsen

    1. Department of Nephrology, University Hospital, Odense C, Denmark

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  3. N. A. Halasz

    1. Department of Surgery, University of California Medical Center, San Diego, USA

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Table of contents (61 chapters)

  1. Front Matter

    Pages i-xxi
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  2. Basic Reviews

    1. Front Matter

      Pages 1-1
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    2. Energetics and mitochondria

      • H. Feinberg
      Pages 3-15
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    3. Membrane functions

      • M. J. Pringle
      Pages 17-25
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    4. Biological significance and therapeutic potential of prostacyclin

      • S. Moncada, J. R. Vane
      Pages 27-32
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    5. A free radical approach to tissue injury

      • H. H. Thaw, J. O. Forsberg, R. F. Del Maestro, B. Gerdin, F. N. McKenzie, K.-E. Arfors
      Pages 33-42
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    6. Endothelial cell function and organ preservation ex vivo

      • J. D. Pearson, A. Hutchings, J. L. Gordon
      Pages 43-54
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    7. The principles of organ storage procedures

      • D. E. Pegg
      Pages 55-66
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  3. Effects of Ischaemia and Anoxia

    1. Front Matter

      Pages 67-67
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    2. Recovery of renal function in the rat after warm ischaemia: functional and morphological changes

      • V. Marshall, P. Jablonski, B. Howden, E. Leslie, D. Rae, J. Tange
      Pages 69-76
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    3. The dynamics of regional blood flow after ischaemic trauma of the rat kidney

      • L. Frödin, L. Karlberg, Ö. Källskog, B. J. Norlén, M. Wolgast
      Pages 77-81
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    4. Renal function impairment in swelling with and without anoxia

      • J. Jamart, L. Lambotte
      Pages 83-89
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    5. Prostacyclin and the ischaemic kidney

      • A. R. Mundy, J. M. Restorick, M. Bewick
      Pages 91-95
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    6. Kidney blood flow and microcirculatory changes after autologous kidney transplantation

      • H. Wilms, E. Sinagowitz
      Pages 97-100
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  4. Biochemical and Pharmacological Aspects of Hypothermia

    1. Front Matter

      Pages 101-101
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    2. Future prospects in organ preservation

      • B. D. Ross
      Pages 103-108
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    3. Tissue pH changes in renal preservation

      • P. Sehr, P. Bore, K. Thulborn, I. Papatheofanis, L. Chan, G. K. Radda
      Pages 109-112
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    4. Study of human kidneys prior to transplantation by phosphorus nuclear magnetic resonance

      • L. Chan, M. E. French, D. G. Gadian, P. J. Morris, G. K. Radda, P. J. Bore et al.
      Pages 113-119
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    5. Effects of hypothermia on anabolic and catabolic processes and on oxygen consumption in perfused rat livers

      • F. A. Zimmermann, H. G. Dietz, Ch. O. Köhler, N. Kilian, J. Kosterhon, R. Scholz
      Pages 121-126
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    6. Mechanism of loss of mitochondrial functions during hypothermic storage of kidneys

      • J. H. Southard, R. M. Hoffmann, F. O. Belzer
      Pages 127-131
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Keywords

About this book

During the past 10 years, there have been many international meetings on the storage of organs prior to transplantation, and several have led to the publication of proceedings; there have also been a number of other books on this subject-. Most of these publications have concentrated on practical clinical aspects of organ preservation and on empirical animal experiments directed towards well-defined clinical objectives. Progress was rapid at first, but it is now generally agreed that there has been little improvement in techniques during the past 5 years, although understanding has certainly increased. In 1980 the Tissue Preservation and Banking Committee of the Transplantation Society decided that a fresh approach to the problem of improving preservation methods was needed: it was decided to hold a conference at which an opportunity would be provided to return to basic principles and to examine some of the advances that have occurred in recent yelns in areas of physiology that might be important for further improvements in preservation. The conference was held in Cambridge, UK, in April 1981 and this book is based upon the papers presented to that meeting and the work of a small discussion group that met after the main meeting. The book starts with six basic review chapters, followed by sections on the effects of ischaemia and anoxia, and on biochemical and pharmacological aspects of hypothermia. Chapters dealing with organ preservation by initial perfusion followed by hypothermia, and by continuous hypothermic perfusion, follow.

Editors and Affiliations

  • MRC Medical Cryobiology Group, University Department of Surgery, Cambridge, UK

    D. E. Pegg

  • Department of Nephrology, University Hospital, Odense C, Denmark

    I. A. Jacobsen

  • Department of Surgery, University of California Medical Center, San Diego, USA

    N. A. Halasz

Bibliographic Information

  • Book Title: Organ Preservation

  • Book Subtitle: Basic and Applied Aspects A Symposium of the Transplantation Society

  • Editors: D. E. Pegg, I. A. Jacobsen, N. A. Halasz

  • DOI: https://doi.org/10.1007/978-94-011-6267-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1982

  • Softcover ISBN: 978-94-011-6269-2Published: 17 February 2012

  • eBook ISBN: 978-94-011-6267-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XXI, 433

  • Topics: Surgery

  • Industry Sectors: Biotechnology, Finance, Business & Banking, Health & Hospitals, Pharma

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