Medico-Social Management of Inherited Metabolic Disease

A Monograph Derived from The Proceedings of the Thirteenth Symposium of The Society for the Study of Inborn Errors of Metabolism

  • D. N. Raine

Table of contents

  1. Front Matter
    Pages i-x
  2. The Nature and Size of the Problem

  3. Present Methods of Management

    1. Front Matter
      Pages 43-43
    2. G. M. Komrower
      Pages 45-50
    3. Christine Clothier
      Pages 51-61
    4. Erik Wamberg
      Pages 63-78
  4. Community Reaction to Present Practice

    1. Front Matter
      Pages 79-79
    2. P. R. Evans
      Pages 93-101
    3. Valerie A. Cowie
      Pages 103-117
  5. Aspects of Management Requiring Central Policy

    1. Front Matter
      Pages 141-141
    2. T. W. Meade
      Pages 143-148
    3. A. Westwood
      Pages 167-196
    4. A. D. Patrick
      Pages 197-215
    5. F. P. Hudson, Janet Hawcroft
      Pages 217-224
    6. A. J. Hedley
      Pages 225-246
    7. Joan S. Emmerson, D. N. Raine
      Pages 247-258
    8. D. N. Raine, Nansi G. Rees, Susan H. Terry
      Pages 259-271
  6. The Fourth Milner Lecture

  7. Back Matter
    Pages 301-310

About this book


The study of inherited metabolic disease became a subject of more than academic interest in 1953 when Bickel, Gerrard and Hickmans dis­ covered that the totally disabling consequences of phenylketonuria could be prevented if treatment was instituted in the first months of life. This required the widespread screening of all newborn babies and 7 years later this had been successfully achieved in the United King­ dom. The next 10 years was a period of consolidation: screening methods were improved and extended to include other disorders; treatment of phenylketonuria was vastly improved with the stimulus of the increasing numbers of patients being detected, and research into new forms of therapy for some of the other disorders being detected has been initiated. The success of this scheme is illustrated by the remarkable achievement reported by the Phenylketonuria Registry referred to in the present volume. But at what cost has this progress been made? It is unnecessary to discuss the financial cost for many of the developments would not have been started if their economic value in the system of health care had not been unequivocally established.


development metabolic disease metabolism newborn nutrition

Editors and affiliations

  • D. N. Raine
    • 1
  1. 1.Department of Clinical ChemistryThe Children’s HospitalBirminghamUK

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1977
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-011-6175-6
  • Online ISBN 978-94-011-6173-2
  • Buy this book on publisher's site
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