Delayed Preconditioning and Adaptive Cardioprotection

  • G. F. Baxter
  • D. M. Yellon

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 207)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. G. F. Baxter, D. M. Yellon
    Pages 1-28
  3. R. Bolli, B. Dawn, X.-L. Tang, Y. Qiu, P. Ping, J. Zhang et al.
    Pages 29-46
  4. V. Richard, P. Beauchamp, N. Kaeffer, C. Thuillez
    Pages 47-62
  5. A. Vegh, J. R. Parratt
    Pages 63-89
  6. R. W. Currie, J.-C. L. Plumier
    Pages 135-153
  7. A. Dana, D. M. Yellon, G. F. Baxter
    Pages 189-207
  8. F. Ottani, M. Galvani, D. Ferrini
    Pages 209-224
  9. Back Matter
    Pages 225-230

About this book

Introduction

Interest in the ability of myocardium to adapt to ischaemic stress has continued to grow since the discovery of ischaemic preconditioning in 1986. In 1993, two reports heralded the recognition of a delayed preconditioning response in the heart, now commonly known as the `second window' of protection. Since then, a number of studies have described the ability of delayed preconditioning and related adaptive phenomena to protect against a variety of pathologies in the ischaemic and reperfused myocardium. Our understanding of the cellular mechanisms of sub-acute adaptive cardioprotection has advanced considerably during this period. This compilation of state-of-the-art reviews by those who have made significant contributions to this field provides detailed and critical analysis of this research, from molecular basis to potential clinical relevance. The book aims to provide an authoritative, comprehensive and thoroughly up-to-date overview for scientists and clinicians engaged in, or observing, this rapidly-developing area of heart research. It will also be of interest to those engaged in research on other tissues where ischaemia-reperfusion pathology is of major concern.

Keywords

adaptation arrhythmia endothelium heart tissue

Editors and affiliations

  • G. F. Baxter
    • 1
  • D. M. Yellon
    • 2
  1. 1.The Hatter Institute for Cardiovascular StudiesUniversity College London Medical SchoolLondonUK
  2. 2.The Hatter Institute for Cardiovascular StudiesUniversity College London Medical SchoolLondonUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-011-5312-6
  • Copyright Information Kluwer Academic Publishers 1998
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6231-2
  • Online ISBN 978-94-011-5312-6
  • Series Print ISSN 0166-9842
  • About this book
Industry Sectors
Biotechnology
Pharma