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  • Book
  • © 1997

Selected Topics in Mass Spectrometry in the Biomolecular Sciences

Editors:

  1. Richard M. Caprioli

    1. Medical School, University of Texas, Houston, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Antonio Malorni

    1. SESMA-C.N.R., Napoli, Italy

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    You can also search for this editor in PubMed   Google Scholar

  3. Giovanni Sindona

    1. Dipartimento di Chimica, Arcavacata di Rende, Università della Calabria, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato Science Series C: (ASIC, volume 504)

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Table of contents (30 chapters)

  1. Application to Biomolecules

    1. Folding Pathways of Disulphide Containing Proteins

      • Margherita Ruoppolo, Fabio Talamo, Piero Pucci, Gennaro Marino
      Pages 347-359

    3. PSD-MALDI Analysis of Peptides

      • B. Spengler
      Pages 377-398

    4. Development of a Mass Spectrometric Approach for the Characterisation of Hemoglobin Adducts

      • Pasquale Ferranti, Nicola Sannolo, Gianfranco Mamone, Giuseppe Forte, Antonio Malorni
      Pages 399-411

    5. Reactivity of Antineoplastic Drugs with Model Peptides Studied by Advanced Mass Spectrometry Methodologies

      • Virginia Carbone, Gabriella Pocsfalvi, Nicola Sannolo, Antonio Malorni
      Pages 413-425

    7. MALDI Mass Analysis of Oligonucleotides

      • U. Bahr, M. Karas
      Pages 455-464

    8. DNA Adducts in Human Carcinogenesis

      • H. Bartsch
      Pages 465-476

    9. MALDI MS of Oligo and Polysaccharides

      • D. Garozzo
      Pages 477-499

    10. Mass Spectrometry of Isoeicosanoids as Novel Lipid Substances

      • Robert C. Murphy, Russell J. Waugh
      Pages 501-515

    11. The Role of Mass Spectrometry in the Characterization of Plant Metabolites from Crude Extracts

      • Antonio De Nino, Anna Napoli, Giovanni Sindona
      Pages 517-531

  2. Back Matter

    Pages 581-586
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About this book

Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases.
Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section.
Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph.D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories.
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Keywords

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Editors and Affiliations

  • Medical School, University of Texas, Houston, USA

    Richard M. Caprioli

  • SESMA-C.N.R., Napoli, Italy

    Antonio Malorni

  • Dipartimento di Chimica, Arcavacata di Rende, Università della Calabria, Italy

    Giovanni Sindona

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Bibliographic Information

  • Book Title: Selected Topics in Mass Spectrometry in the Biomolecular Sciences

  • Editors: Richard M. Caprioli, Antonio Malorni, Giovanni Sindona

  • Series Title: Nato Science Series C:

  • DOI: https://doi.org/10.1007/978-94-011-5165-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1997

  • Hardcover ISBN: 978-0-7923-4849-8Published: 31 December 1997

  • Softcover ISBN: 978-94-010-6171-1Published: 09 November 2012

  • eBook ISBN: 978-94-011-5165-8Published: 06 December 2012

  • Series ISSN: 1389-2185

  • Edition Number: 1

  • Number of Pages: XXVI, 586

  • Topics: Mass Spectrometry, Analytical Chemistry, Biochemistry, general

  • Industry Sectors: Biotechnology, Chemical Manufacturing

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Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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