© 2000

Helicobacter pylori

Basic Mechanisms to Clinical Cure 2000

  • Richard H. Hunt
  • Guido N. J. Tytgat

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Helicobacter pylori — The organism

    1. Front Matter
      Pages 1-1
    2. D. L. Weeks, D. R. Scott, P. Voland, E. A. Marcus, C. Athmann, K. Melchers et al.
      Pages 15-24
  3. Helicobacter pylori — Epidemiology

  4. Novel Helicobacters

  5. Diagnosis of Helicobacter pylori infection

    1. Front Matter
      Pages 113-113
    2. D. Vaira, C. Ricci, M. Menegatti, C. Acciardi, L. Gatta, A. Geminiani et al.
      Pages 115-122
    3. P. Malfertheiner, A. Leodolter, C. Gerards
      Pages 123-138
  6. Inflammation and the Immune Response toHelicobacter pylori Infection

    1. Front Matter
      Pages 139-139

About this book


The fourth meeting in the very successful series Helicobacter pylori: Basic Mechanisms to Clinical Cure was held on the island of Bermuda in late March 2000. This was only some two years after the third meeting in San Diego and it seemed hardly possible that there would be so much new information. However, as the contributions in this volume testify, there was plenty of exciting new information with important implications for both understanding this infection and for clinical management. Some of this information was of a fundamental nature, such as the role of the acid­ sensitive urel channel in regulating the influx of urea and the formation of ammonia transported back in the microbial periplasmic space to neutralize acid; the observation of genetic polymorphism of the IL-1~ gene as an explanation of achlorhydria and gastric cancer risk in the first-degree relatives of gastric cancer patients; and the peculiar biochemical and physio­ logical consequences of the genome of the microorganisms. The format of the meeting, with short fifteen-minute state-of-the-art pre­ sentations by world experts closely involved in Helicobacter research fol­ lowed by ample time for panel discussions, was again followed this year. Traditional aspects included detailed study of the microbial characteristics, the novel Helicobacters, the interaction with the human host, the peculiarities of the inflammatory immune response, the short and long-term mucosal consequences, the effects on acid secretion, the problem of gastric malignancy and the therapeutic possibilities.


Gastritis antigen cancer gene helicobacter pylori infection vaccine

Editors and affiliations

  • Richard H. Hunt
    • 1
  • Guido N. J. Tytgat
    • 2
  1. 1.Division of GastroenterologyMcMaster University Medical CentreHamiltonCanada
  2. 2.Department of Gastroenterology and HepatologyAcademic Medical CentreAmsterdamThe Netherlands

Bibliographic information

  • Book Title Helicobacter pylori
  • Book Subtitle Basic Mechanisms to Clinical Cure 2000
  • Editors R.H. Hunt
    G.N. Tytgat
  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2000
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-7923-8764-0
  • Softcover ISBN 978-94-010-5753-0
  • eBook ISBN 978-94-011-3927-4
  • Edition Number 1
  • Number of Pages XXII, 689
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Gastroenterology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


`This book provides an extensive compendium of information(with an index) on the recent developments in the broad range of investigations into H.pylori and its varions manifestations. It will be a valuable, up-to-date resource for gastroentelogists, microbiologists, and anyone interested in H.pylori.'
Helicobacter pylori: Basic Mechanisms to Clinical Cure 200 (2000)