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© 1993

Applications of Supercritical Fluids in Industrial Analysis

  • John R. Dean
Book

Table of contents

  1. Front Matter
    Pages i-xiv
  2. S. M. Hitchen, J. R. Dean
    Pages 1-11
  3. J. R. Dean, M. Kane
    Pages 46-73
  4. I. D. Wilson, P. Davis, R. J. Ruane
    Pages 74-103
  5. D. E. Knowles, T. K. Hoge
    Pages 104-129
  6. V. Janda, K. Bartle, A. A. Clifford
    Pages 159-187
  7. Back Matter
    Pages 219-224

About this book

Introduction

The continued search for rapid, efficient and cost-effective means of analytical measurement has introduced supercritical fluids into the field of analytical chemistry. Two areas are common: supercritical fluid chroma­ tography and supercritical fluid extraction. Both seek to exploit the unique properties of a gas at temperatures and pressures above the critical point. The most common supercritical fluid is carbon dioxide, employed because of its low critical temperature (31 °C), inertness, purity, non-toxicity and cheapness. Alternative supercritical fluids are also used and often in conjunction with modifiers. The combined gas-like mass transfer and liquid-like solvating characteristics have been used for improved chroma­ tographic separation and faster sample preparation. Supercritical fluid chromatography (SFC) is complementary to gas chro­ matography ( GC) and high performance liquid chromatography (HPLC), providing higher efficiency than HPLC, together with the ability to analyse thermally labile and high molecular weight analytes. Both packed and open tubular columns can be employed, providing the capability to analyse a wide range of sample types. In addition, flame ionization detection can be used, thus providing 'universal' detection.

Keywords

Atom Chromat Lipid chromatography extraction pharmaceutical chemistry polymer supercritical fluid

Editors and affiliations

  • John R. Dean
    • 1
  1. 1.Department of Chemical and Life SciencesUniversity of Northumbria at NewcastleUK

Bibliographic information

  • Book Title Applications of Supercritical Fluids in Industrial Analysis
  • Authors J.R. Dean
  • DOI https://doi.org/10.1007/978-94-011-2146-0
  • Copyright Information Chapman & Hall 1993
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-7514-0057-1
  • Softcover ISBN 978-94-010-4951-1
  • eBook ISBN 978-94-011-2146-0
  • Edition Number 1
  • Number of Pages XIV, 224
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Analytical Chemistry
    Organic Chemistry
    Physical Chemistry
  • Buy this book on publisher's site
Industry Sectors
Biotechnology
Chemical Manufacturing
Consumer Packaged Goods
Pharma

Reviews

...well organized and edited and can be recommended to those who want to apply SFC/SFE in their work. - Trends in Analytical Chemistry.; In conclusion, the book makes a useful contribution in transfering supercritical fluid methods from a basic study area to an application that solves real problems. - Chemistry in Britain