© 1993

Ischemia-reperfusion in cardiac surgery

  • Hans Michael Piper
  • Claus J. Preusse

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 142)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pathophysiology of ischemia and reperfusion

    1. Front Matter
      Pages 1-1
    2. Marcel E. Zughaib, Paul B. McCay, Mohamed O. Jeroudi, Craig Hartley, Jian-Zhong Sun, Selim Sekili et al.
      Pages 3-40
    3. Hans Michael Piper, Berthold Siegmund, Klaus-Dieter Schlüter
      Pages 41-66
    4. Sharon L. Hale, Robert A. Kloner
      Pages 67-80
    5. Flavian M. Lupinetti
      Pages 81-103
  3. Concepts of cardioplegia

    1. Front Matter
      Pages 105-105
    2. Claus J. Preusse
      Pages 107-134
    3. David John Chambers, Mark Viney Braimbridge
      Pages 135-179
    4. Gerald D. Buckberg, Bradley S. Allen, Friedhelm Beyersdorf
      Pages 181-227
  4. Clinical application of cardioplegia

    1. Front Matter
      Pages 229-229
    2. Irvin B. Krukenkamp, Christopher A. Caldarone, Paul Burns, Sidney Levitsky
      Pages 231-242
    3. Hagen D. Schulte
      Pages 243-253
    4. Philippe Menasche
      Pages 255-266
    5. Cary W. Akins
      Pages 267-278
    6. John E. Mayer Jr.
      Pages 279-291
  5. Evaluation of cardioplegic methodology

    1. Front Matter
      Pages 293-293
    2. Jan Willem De Jong, Tom Huizer, Maarten Janssen, Rob Krams, Monique Tavenier, Pieter D. Verdouw
      Pages 295-315
    3. Ernst-Georg Krause, Dorothea Pfeiffer, Ulla Wollenberger, Hans-Georg Wollert
      Pages 317-333

About this book


In open heart surgery, protection of the myocardium against injury by ischemia-reperfusion is an issue of utmost clinical interest. The knowledge on the causal mechanisms of myocardial injury in ischemia-reperfusion has greatly progressed in recent years, both to clinical and experimental research. This book provides a critical and comprehensive overview on the current discussion of myocardial protection in cardiac experimental research and surgery. Leading groups from Europe, the U.S. and Japan have contributed reviews of their special fields.
On the basic science side, major topics discussed are the mechanisms of stunning and lethal reperfusion injury, the role of the endothelium and leukocyte activation in postischemic myocardial dysfunction, and the differences between the adult and neonatal myocardium. On the clinical side, the major concepts and procedures for cardioplegic myocardial protection, their rationales, application and respective merits are discussed. In a third part of the book, possible approaches for the monitoring of myocardial injury during ischemia and reperfusion are evaluated, with particular attention to their intraoperative use.
This book brings together the scientific discussions on ischemia-reperfusion in experimental cardiology and cardiac surgery, a task needed for a long time. It is of general interest for clinicians as well as research workers and students in the cardiac field.


Bypass cardiac function cardiac surgery cardiology heart physiology

Editors and affiliations

  • Hans Michael Piper
    • 1
  • Claus J. Preusse
    • 2
  1. 1.Institute of PhysiologyHeinrich-Heine-UniversityDüsseldorfGermany
  2. 2.Department of Thoracic and Cardiovascular SurgeryHeinrich-Heine-UniversityDüsseldorfGermany

Bibliographic information

  • Book Title Ischemia-reperfusion in cardiac surgery
  • Editors Hans Michael Piper
    C.J. Preusse
  • Series Title Developments in Cardiovascular Medicine
  • DOI
  • Copyright Information Kluwer Academic Publishers 1993
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-7923-2241-2
  • Softcover ISBN 978-94-010-4750-0
  • eBook ISBN 978-94-011-1713-5
  • Series ISSN 0166-9842
  • Edition Number 1
  • Number of Pages XIII, 458
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cardiac Surgery
    Thoracic Surgery
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Surgery & Anesthesiology