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The Cornea in Normal Condition and in Groenouw’s Macular Dystrophy

  • Jules François
  • Virgilio Victoria-Troncoso
Book

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Introduction

    1. Jules François, Virgilio Victoria-Troncoso
      Pages 2-3
  3. Normal Keratocytes

    1. Front Matter
      Pages 5-5
    2. Jules François, Virgilio Victoria-Troncoso
      Pages 7-36
    3. Jules François, Virgilio Victoria-Troncoso
      Pages 37-44
    4. Jules François, Virgilio Victoria-Troncoso
      Pages 45-60
    5. Jules François, Virgilio Victoria-Troncoso
      Pages 61-77
    6. Jules François, Virgilio Victoria-Troncoso
      Pages 79-92
  4. Pathologic Keratocytes (Macular Dystrophy of the Cornea)

    1. Front Matter
      Pages 93-93
    2. Jules François, Virgilio Victoria-Troncoso
      Pages 95-96
    3. Jules François, Virgilio Victoria-Troncoso
      Pages 99-112
    4. Jules François, Virgilio Victoria-Troncoso
      Pages 113-121
    5. Jules François, Virgilio Victoria-Troncoso
      Pages 123-125
    6. Jules François, Virgilio Victoria-Troncoso
      Pages 139-150
    7. Jules François, Virgilio Victoria-Troncoso
      Pages 151-155
    8. Jules François, Virgilio Victoria-Troncoso
      Pages 157-159
    9. Jules François, Virgilio Victoria-Troncoso
      Pages 177-181
    10. Jules François, Virgilio Victoria-Troncoso
      Pages 183-183
  5. Summary

    1. Jules François, Virgilio Victoria-Troncoso
      Pages 185-187
  6. Back Matter
    Pages 188-200

About this book

Introduction

The three most striking characteristics of the cornea are: a) Its structure or rather its perfectly regular architectonic, by virtue of which it is transparent. b) The absence of vessels, the cornea being nourished by the perilimbic vessels, the endothelial surface in communication with the aqueous humour and the epithelial surface in contact with the pre-corneal film. c) The very slow turnover of the cells, that is to say the keratocytes, with the result that the metabolism of the cornea is very weak. It is this third characteristic which justifies our present investigation. The keratocytes, which are apparently inactive, have in fact a latent activity. They can be activated by central corneal incisions and also by tissue cultures. Under either of those conditions, the keratocytes become very active, develop all the cytoplasmic organites and produce mucopoly­ saccharides as well as the precursors of the collagen (Fig. 1). In order to study the pathological keratocyte, we chose a storage disease, wherein the catabolism of the mucopolysaccharides is blocked, namely the macular dystrophy of the cornea. We undertook the same investigation both for normal and for pathologi­ cal corneas and studied the keratocyte 'in situ' and in tissue cultures using various microscopical and histochemical techniques. In macular dystrophy, we investigated also the deteriorations secondary to the changes in the keratocytes.

Keywords

X-ray cell chemistry communication evolution growth heredity implant implantat membrane pathogenesis polysaccharides tissue transmission electron microscopy treatment

Authors and affiliations

  • Jules François
    • 1
  • Virgilio Victoria-Troncoso
  1. 1.Ophthalmological Clinic of the University of GhentBelgium

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-009-9177-4
  • Copyright Information Springer Science+Business Media B.V. 1980
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-009-9179-8
  • Online ISBN 978-94-009-9177-4
  • Buy this book on publisher's site
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