© 1982



About this book


The increased interest in multiple forms of enzymes that began with the application of new methods of fractionation to preparations of enzymes and other proteins some 25 years ago led quickly to an appreciation that the existence of enzymes in multiple forms, or isoenzymes, is a general phenomenon. The results of pioneering studies and those which followed in the early years of isoenzyme research consisted, not surprisingly, mainly of descriptions of the existence and characteristics of hetero­ geneity in various enzyme systems. Summaries of these results were provided in books such as J . H. Wilkinson's I soenzymes, the first edition of which appeared in 1965. Some clearer ideas of the nature of the phenomena had become apparent by the time that the second edition of Isoenzymes was called for in 1970, and a limited use of the word isoenzymes itself, to describe only certain of the various categories of enzyme multiplicity then recognized, was already being proposed. Nevertheless, a largely enzyme-by-enzyme oTganization of the contents of the book was still appropriate. Considerable advances, both experimental and conceptual, were made in isoenzyme research in the 1970s, and in 1977 Professor Wilkinson suggested to the present author that these should be taken into account in a joint revision of Isoenzymes. Professor Wilkinson's untimely death put. an end to this project and the present book is therefore the work of a single author.


activation biological enzyme enzymology evolution gene genes hydrogen peptide phylogeny plants proteins quaternary structure stability structure

Authors and affiliations

  1. 1.Royal Postgraduate Medical SchoolHammersmith HospitalLondonUK

Bibliographic information

  • Book Title Isoenzymes
  • Authors D. W. Moss
  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1982
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-412-22200-9
  • Softcover ISBN 978-94-009-5888-3
  • eBook ISBN 978-94-009-5886-9
  • Edition Number 1
  • Number of Pages XII, 204
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Science, Humanities and Social Sciences, multidisciplinary