Psychobiology of Stress

  • Stefan Puglisi-Allegra
  • Alberto Oliverio

Part of the NATO ASI Series book series (ASID, volume 54)

Table of contents

  1. Front Matter
    Pages i-viii
  2. P. R. Wiepkema
    Pages 1-13
  3. Klaus A. Miczek, Michael L. Thompson, Walter Tornatzky
    Pages 15-30
  4. Adrian J. Dunn, Craig W. Berridge
    Pages 81-93
  5. Pierre Mormède
    Pages 95-102
  6. B. Bohus, J. M. Koolhaas, C. Nyakas, P. G. M. Luiten, C. A. M. Versteeg, S. M. Korte et al.
    Pages 103-123
  7. Filippo Drago, Francesco Spadaro, Velia D’Agata, Teresa Iacona, Carmela Valerio, Rocco Raffaele et al.
    Pages 125-133
  8. F. R. Patacchioli, L. Angelucci
    Pages 135-142
  9. Seymour M. Antelman, Anthony R. Caggiula
    Pages 161-170
  10. Stefano Puglisi-Allegra, Simona Cabib, Eliane Kempf, Alberto Oliverio
    Pages 171-182
  11. S. Algeri, L. Biagini, P. Garofalo, M. Marconi, N. Pitsikas, G. Sacchetti
    Pages 183-190
  12. Michel Cabanac
    Pages 203-209
  13. Arnold J. Wilkins
    Pages 211-221
  14. D. Naber, M. Bullinger, R. Holzbach, G. Oliveri, T. Schmitt, E. Klein et al.
    Pages 223-229
  15. G. Robert, J. Hockey, Marion Wiethoff
    Pages 231-239
  16. Back Matter
    Pages 251-256

About this book


From a historical point of view the first studies on the response of the organism to stressful situations in general, and on the psychobiology of stress in particular, are probably those of Cannon and de la Paz, the physiologists who showed in 1911 that the adrenal medulla and the sympathetic system are involved in emergency situations. Cannon noted that the venous blood of cats frightened by barking dogs contained adrenaline, a response of the organism which was prevented by adrenalectomy or by section of the splanchnic nerve innervating the adrenal medulla. Cannon suggested that the adrenal medulla was acting in concert with the sympathetic nervous system, so that both systems were activated during stress. The role of the sympathetic system in response to stressful events was later emphasized by the experiments carried out by Maickel et al. (1967) and by Mason (1968): these authors clearly showed that stressors activate the sympathetic system causing it to release adrenaline and noradrenaline. This line of research may be contrasted with that carried out by Hans Selye, centered on of the adrenal cortex in the stress response. Selye's findings and theories originated the role the so-called hypothalamic - pituitary - adrenal cortex (HPA) model of stress: in short, during stress adrenocorticotropic hormone is released from cells of the anterior pituitary and elicits secretion of glucocorticoids from the adrenal cortex.


Affective Neuroscience behavior brain dopamine neuropeptides neuroscience receptor stress

Editors and affiliations

  • Stefan Puglisi-Allegra
    • 1
  • Alberto Oliverio
    • 2
  1. 1.Institute of Psychobiology and PsychopharmacologyNational Research Council of Italy (C.N.R.)RomeItaly
  2. 2.Department of Genetics and Molecular BiologyUniversity of RomeRomeItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1990
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-7390-5
  • Online ISBN 978-94-009-1990-7
  • Series Print ISSN 0258-123X
  • Buy this book on publisher's site
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