From Cell Biology to Pharmacology and Therapeutics

  • Rodolfo Paoletti
  • Paul M. Vanhoutte
  • Nicoletta Brunello
  • Franco M. Maggi

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Serotonin Research: Historical Overview

    1. M. M. Rapport
      Pages 1-4
  3. Molecular Mechanisms in Serotonin Mediated Response

    1. Front Matter
      Pages 5-5
    2. M. Hamon, S. El Mestikawy, M. B. Emerit, H. Gozlan
      Pages 13-17
    3. A. Fargin, J. R. Raymond, R. J. Lefkowitz, M. G. Caron
      Pages 19-24
    4. D. De Chaffoy De Courcelles, F. De Clerck
      Pages 25-31
    5. Saul Maayani, Merry R. Sherman
      Pages 39-51
    6. S. Z. Langer, C. R. Lee, H. Esnaud, D. Graham
      Pages 53-60
  4. Physiology of Serotonergic System

    1. Front Matter
      Pages 67-67
    2. Vascular System

      1. W. J. Janssens, J. M. Van Nueten
        Pages 69-76
      2. F. De Clerck, D. De Chaffoy De Courcelles
        Pages 77-80
      3. P. M. Vanhoutte, J. M. Van Nueten, W. J. Janssens
        Pages 81-96
      4. Hiroaki Shimokawa, Nicholas A. Flavahan, Paul M. Vanhoutte
        Pages 97-104
      5. Ch. Owman, J.-Y. Chang, J. E. Hardebo, H. W. M. Steinbusch
        Pages 105-115
      6. A. Pletscher, N. Fetkovska, F. Ferracin, R. Amstein, F. R. Buehler
        Pages 117-121
      7. Louis D. Van de Kar, Janice H. Urban, Mark S Brownfield
        Pages 123-129
      8. Tony J. Verbeuren
        Pages 131-135
      9. Donald D. Heistad, J. Antonio G. Lopez, William G. Mayhan
        Pages 137-140
    3. Central Nervous System

      1. Staffan Cullheim, Ulf Arvidsson, Brun Ulfhake, Tomas Hökfelt, Johan Christenson, Lennart Brodin et al.
        Pages 149-154
      2. M. L. Barbaccia, P. L. Wood, E. Costa
        Pages 155-159
      3. M. Raiteri, G. Maura, G. Bonanno, A. Pittaluga, E. Fedele, C. Costa et al.
        Pages 161-168
      4. K. Fuxe, L. F. Agnati, G. Von Euler, K. Lundgren, M. Zoli, B. Bjelke et al.
        Pages 169-185
      5. S. Garattini, S. Caccia, T. Mennini, R. Samanin
        Pages 193-202
      6. Sarah F. Leibowitz, Gail Shor-Posner, Gail F. Weiss
        Pages 203-211
    4. Gastrointestinal System

      1. Karsten Bech, Bjarne Johansen
        Pages 229-233
      2. Bernard M. Jaffe
        Pages 235-239
  5. Serotonergic Receptors: Biochemistry, Physiology and Pharmacology

    1. Front Matter
      Pages 257-257
    2. G. K. Aghajanian, J. S. Sprouse, P. Sheldon, K. Rasmussen
      Pages 277-282
    3. Robert J. Walker, Agnes Vehovszky
      Pages 283-288
    4. D. N. Middlemiss, W. C. Lee, S. M. Smith, M. D. Tricklebank
      Pages 301-307
    5. Elaine Sanders-Bush, Manami Tsutsumi
      Pages 309-315
    6. J. R. Fozard
      Pages 331-338
    7. G. J. Kilpatrick, B. J. Jones, M. B. Tyers
      Pages 339-345
    8. Alberto J. Kaumann, Ken J. Murray, Anthony M. Brown, James E. Frampton, Louise Sanders, Morris J. Brown
      Pages 347-354
    9. Marlene L. Cohen, Roberta J. Secrest, Raymond F. Kauffman
      Pages 355-359

About this book


This volume represents the proceedings ofthe invited lectures ofthe first International Symposium on "Serotonin from Cell Biology to Pharmacology and Therapeutics" which was held in Florence on March 29 -Aprill, 1989. This meeting, held under the co-sponsorship of the Serotonin Club and the Fondazione Giovanni Lorenzini, represents the first attempt to bring together scientists fascinated by the complexity of the action of 5-hydroxytryptamine throughout the body and in various species. Hence this volume provides the reader with the unique overview of the sources, effects, receptors, physiological actions and pathological role of Serotonin. As such it will be of interest not only to the person devoting herorhis research efforts to the study of 5-hydroxytryptamine but also to all scholars and even clinicians wanting to know how the powerful monoamine can modulate cellular functions. To accelerate the publication of these proceedings the Editors and the publishers have selected the camera ready format and have avoided a lengthy refereeing process. Hence the scientific content of, and the opinions expressed in the chapters are the sole responsibility of the authors. The Editors Milan and Houston The Editors want to thank Mrs. H. Liepman and her staff at Kluwer for the prompt and efficient handling of the manuscripts.


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Editors and affiliations

  • Rodolfo Paoletti
    • 1
  • Paul M. Vanhoutte
    • 2
  • Nicoletta Brunello
    • 3
  • Franco M. Maggi
    • 3
  1. 1.Fondazione LorenziniMilanItaly
  2. 2.Mayo ClinicRochesterUSA
  3. 3.Institute of Pharmacological SciencesUniversity of MilanItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1990
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-7353-0
  • Online ISBN 978-94-009-1912-9
  • Buy this book on publisher's site
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