© 2013

Biomechanics of Cells and Tissues

Experiments, Models and Simulations

  • Paola Lecca


  • Includes recent advances on experimental and bioengineering techniques

  • Focuses on cell mechanics models suitable for computer simulations and analysis

  • Incorporates applications and examples


Part of the Lecture Notes in Computational Vision and Biomechanics book series (LNCVB, volume 9)

Table of contents

  1. Front Matter
    Pages i-vii
  2. C. P. Laurent, D. Durville, C. Vaquette, R. Rahouadj, J.-F. Ganghoffer
    Pages 1-44
  3. Ozan Kahramanoğulları, Andrew Phillips, Federico Vaggi
    Pages 45-63
  4. Paola Lecca, Gabriela Constantin, Carlo Laudanna, Corrado Priami
    Pages 65-80
  5. Miroslava Cuperlovic-Culf, Pier Morin Jr, Natalie Lefort
    Pages 81-102
  6. Back Matter
    Pages 157-168

About this book


The application of methodological approaches and mathematical formalisms proper to Physics and Engineering to investigate and describe biological processes and design biological structures has led to the development of many disciplines in the context of computational biology and biotechnology. The best known applicative domain is tissue engineering and its branches. Recent domains of interest are in the field of biophysics, e.g.: multiscale mechanics of biological membranes and films and filaments; multiscale mechanics of adhesion; biomolecular motors and force generation.


Modern hypotheses, models, and tools are currently emerging and resulting from the convergence of the methods and philosophical approaches of the different research areas and disciplines. All these emerging approaches share the purpose of disentangling the complexity of organisms, tissues, and cells and mimicking the function of living systems.

The contributions presented in this book are current research highlights of six challenging and representative applicative domains of phyisical, engineering, and computational approaches in medicine and biology, i.e tissue engineering, modelling of molecular structures, cell mechanics and cell adhesión processes, cancer physics, and physico-chemical processes of metabolic interactions. Each chapter presents a compendium or a review of the original results achieved by authors  in the last years. Furthermore, the book also wants to pinpoint the questions that are still open and that could propel future research.


biological processes biomechanics cell mechanics cell molecular biology computer simulations material properties mechanobiology mechanotransduction

Editors and affiliations

  • Paola Lecca
    • 1
  1. 1.Centre for Computational Mechanics, Microsoft Research labUniversity of TrentoTrentoItaly

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