© 2012

Tumors of the Central Nervous System, Volume 8

Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma

  • M.A. Hayat

Part of the Tumors of the Central Nervous System book series (TCNS, volume 8)

Table of contents

  1. Front Matter
    Pages i-xxxvii
  2. Astrocytoma

    1. Front Matter
      Pages 1-1
    2. Tomohiro Osanai, Chisato Katoh, Ken Okumura
      Pages 3-11
    3. Kaisorn L. Chaichana, Matthew J. McGirt
      Pages 13-20
  3. Medulloblastoma

    1. Front Matter
      Pages 21-21
    2. Valentina Caracciolo, Antonio Giordano
      Pages 23-33
    3. Austin Mattox, Jing Li, Chunhui Di, D. Cory Adamson
      Pages 47-58
    4. Violaine Sée, Barry Pizer, Daniel Meley
      Pages 59-69
    5. Arnold C. Paulino
      Pages 71-75
    6. Christian Carrie, Marie-Pierre Sunyach
      Pages 85-90
  4. Retinoblastoma

    1. Front Matter
      Pages 91-91
    2. Mariangela Amenduni, Gabriella Livide, Francesca Ariani, Alessandra Renieri
      Pages 93-102
    3. Javier G. Pizarro, Antoni Camins, Felix Junyent, Ester Verdaguer, Carme Auladell, Carlos Beas-Zarate et al.
      Pages 103-115
    4. Hanan Shehata, Azza Abou Ghalia, Eman Elsayed
      Pages 117-124
    5. Domenico Mastrangelo, Cosimo Loré, Giovanni Grasso
      Pages 125-132
    6. Madhavan Jagadeesan, Sudhir Sudrik, Vikas Khetan
      Pages 133-146
    7. Annette C. Moll, Tamara Marees, Machteld I. Bosscha, Flora E. van Leeuwen
      Pages 147-154

About this book


With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma.


Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted—and thus more effective.


Assessment of cancer treatments Cancer diagnosis Cancer drug development Cancer prognosis Cancer therapy

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1., Kean UniversityRoom 213, Library buildingUnionUSA

Bibliographic information

  • Book Title Tumors of the Central Nervous System, Volume 8
  • Book Subtitle Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
  • Editors M.A. Hayat
  • Series Title Tumors of the Central Nervous System
  • DOI
  • Copyright Information Springer Science+Business Media B.V. 2012
  • Publisher Name Springer, Dordrecht
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-94-007-4212-3
  • Softcover ISBN 978-94-024-0601-6
  • eBook ISBN 978-94-007-4213-0
  • Edition Number 1
  • Number of Pages XXXVII, 347
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cancer Research
    Primary Care Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods


From the reviews:

“This volume in the series, Tumors of the Central Nervous System, explores recent developments in tumor biology and newer classification and treatment information for seven distinct types of brain tumors. … The book is written for oncologists, both fellows and practitioners, neuro-oncologists, neurologists, neuropathologists, and neurosurgeons. … In addition to providing an update, the book can also inspire a new generation of researchers in tumor biology and in the design of more effective and scientifically based chemotherapy.” (Ramsis Farid Ghaly, Doody’s Review Service, October, 2012)