Stem Cells and Cancer Stem Cells, Volume 4

Therapeutic Applications in Disease and Injury

  • M.A. Hayat

Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 4)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Molecular Genetic

    1. Front Matter
      Pages 1-1
    2. Charles-Etienne Lebert-Ghali, Joanne Margaret Ramsey, Alexander Thompson, Janetta Bijl
      Pages 19-29
    3. Ryoichiro Kageyama, Hiromi Shimojo, Toshiyuki Ohtsuka, Itaru Imayoshi
      Pages 31-39
    4. Hidefumi Maeda, Shinsuke Fujii, Satoshi Monnouchi, Naohisa Wada, Akifumi Akamine
      Pages 51-58
  3. Regenerative Medicine

    1. Front Matter
      Pages 85-85
    2. Yin Zi, Chen Xiao, Boon Chin Heng, Hong Wei Ouyang
      Pages 87-95
    3. Alexandra L. Rodriguez, David R. Nisbet, Clare L. Parish
      Pages 97-111
    4. Kee Pah Lim, Ling Qian, Philip Wong, Winston Shim
      Pages 161-174
    5. Stefania Mazzitelli, Renata Vecchiatini, Letizia Penolazzi, Elisabetta Lambertini, Roberta Piva, Claudio Nastruzzi
      Pages 175-191
  4. Therapy

    1. Front Matter
      Pages 193-193
    2. Ching-Shwun Lin, Tom F. Lue
      Pages 203-216
    3. Grazia Maria Spaggiari, Lorenzo Moretta
      Pages 217-224
    4. Michael C. Oh, Mitchel S. Berger, Daniel A. Lim
      Pages 225-234
    5. Makiko Ono, Yasuhiro Fujiwara, Takahiro Ochiya
      Pages 249-257
    6. Krzysztof M. Mrozik, Jimin Xiong, Peter S. Zilm, Stan Gronthos, P. Mark Bartold
      Pages 267-284
  5. Transplantations

  6. Back Matter
    Pages 305-319

About this book


It is difficult to overstate the potential applications of stem-cell biology to our understanding of, and responses to, disease and injury. This volume aims to bring to its readers authoritative and responsive coverage of aspects of the field that will keep them up-to-date in a fast-moving scientific landscape. The fourth volume in the series on stem cells and their cancer-carrying counterparts, this book sets out the plethora of therapeutic applications offered by a group of specific stem cells in tackling disease and tissue injury. The list of subjects includes embryonic, induced pluripotent, human hair follicle, bone marrow-derived human mesenchymal, adipose-derived, cancer, and breast cancer stem cells, in addition to periodontal/progenitor cells. The adaptability of human embryonic stem cells, which have the potential to develop into any cell type, ensures them an especially detailed treatment.


Contributions explore the causal influence of cancer stem cells in malignancies such as cancer and breast cancer, and delineate the way mesenchymal stem cells contribute to the growth and metastasis of colon cancer. Shifting from disease to treatment, the text explains the therapeutic value of transplanting mesenchymal stem cells to the injured brain as an aid to its recovery. It includes material, too, on the exciting prospect of valuable new targeted cancer drugs borne of our increasing understanding of the molecular pathways peculiar to tumor biology. Key topics, such as the benefit of stem cell transplantation to immune system recovery among severe combined immunodeficiency patients, and the treatment of malignant gliomas using genetically modified neural stem cells as markers, provide a window on cutting-edge work in these specialized subjects. The extensive scope and detailed analysis of this volume, and of the series to which it belongs, mean that whether readers want a breakdown of the impact being made by cancer stem cell research on the design of next-generation cancer therapies, or details of the way stem cells could transform regenerative medicine by repairing damage to vital organs and tissues, they will find these—and much more—here.


Cancer Stem cells Regenerative Medicine Stem cells Tissue Engineering Tumor development

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1., Kean UniversityRoom 213, Library buildingUnionUSA

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