Cellular Effects of Heavy Metals

  • Gaspar Banfalvi

Table of contents

  1. Front Matter
    Pages 1-1
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Heavy metal toxicity in microbes

    1. Front Matter
      Pages 29-29
    2. Borut Poljsak, István Pócsi, Miklós Pesti
      Pages 59-86
  4. Heavy metal induced toxicity in insect cells

    1. Front Matter
      Pages 113-113
  5. Genotoxic effects of heavy metals

    1. Front Matter
      Pages 145-145
    2. Gábor Nagy, Diána Laza, Kinga Ujvárosi, Gáspár Bánfalvi
      Pages 163-178
    3. Gábor Papp, Gábor Nagy, István Pócsi, Miklós Pesti, Gáspár Bánfalvi
      Pages 179-193
    4. Gábor Nagy, Melinda Turáni, Katalin Éva Kovács, Gáspár Bánfalvi
      Pages 195-217
  6. Chemical Carcinogenesis Induced by Heavy Metals

  7. Cellular Responses to Heavy Metal Exposure

    1. Front Matter
      Pages 261-261
    2. Sandeep K. Sharma, Pierre Goloubinoff, Philipp Christen
      Pages 263-274
  8. Biomarkers

    1. Front Matter
      Pages 313-313
  9. Removal of Heavy Metals

    1. Front Matter
      Pages 331-331
    2. Gábor Szalóki, Ildikó Czégény, Gábor Nagy, Gáspár Bánfalvi
      Pages 333-346
  10. Back Matter
    Pages 330-330

About this book


The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organismal level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mecha nisms such as gene expression, protein folding, stress signalling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.


accumulation apoptosis carcinogenesis genotoxicity removal

Editors and affiliations

  • Gaspar Banfalvi
    • 1
  1. 1., Institute of Biology and EcologyUniversity of DebrecenDebrecenHungary

Bibliographic information

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