© 2011

MicroRNAs in Cancer Translational Research

  • William C.S. Cho


  • MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields

  • Brings together opinion leaders in the miRNA field

  • Comprises 22 in-depth chapters providing up-to-date discoveries of miRNA's


Table of contents

  1. Front Matter
    Pages i-xiii
  2. Manuela Ferracin, George A. Calin, Massimo Negrini
    Pages 1-71
  3. Don L. Gibbons, Zain H. Rizvi, Jonathan M. Kurie
    Pages 73-89
  4. Suvi-Katri Leivonen
    Pages 91-106
  5. Ondrej Slaby, Marek Svoboda, Jaroslav Michalek, Rostislav Vyzula
    Pages 107-133
  6. Hidekazu Suzuki, Yoshimasa Saito, Toshifumi Hibi
    Pages 135-143
  7. Paolo Gandellini, Marco Folini, Nadia Zaffaroni
    Pages 145-162
  8. Junfang Ji, Xin Wei Wang
    Pages 163-188
  9. Jeong-Won Lee, Byoung-Gie Kim, Duk-Soo Bae
    Pages 189-199
  10. Jian Gu, Xifeng Wu
    Pages 201-221
  11. Michael B. Williams, Liana Adam
    Pages 223-237
  12. Alba Navarro López, Luis Hernández Pous
    Pages 239-267
  13. Florian Kuchenbauer, Johannes Bloehdorn, Lars Bullinger, Thorsten Zenz
    Pages 269-285
  14. Chunsheng Li, Yi Feng, George Coukos, Lin Zhang
    Pages 309-342
  15. Tara Spence, Johnny Nguyen, Eric Bouffet, Annie Huang
    Pages 343-371
  16. Zuoren Yu, Richard G. Pestell
    Pages 373-388
  17. Ashhar S. Ali, Shadan Ali, Aamir Ahmad, Philip A. Philip, Fazlul H. Sarkar
    Pages 389-413
  18. Emily J. Noonan, Robert F. Place, Long-Cheng Li
    Pages 415-447
  19. Erik A.C. Wiemer
    Pages 449-483

About this book


MicroRNA (miRNA) is a cutting-edge topic in the scientific and medical fields. This is a timely and specialized book focusing on the current understanding of miRNAs and the potential for their application in cancer diagnosis, prognosis, and therapeutic targets. It also provides discussion of the lessons learned from translational miRNA studies and exploration of the next steps required to advance this field.

The unique book comprises 22 in-depth chapters by gathering unparalleled topics of interest in miRNAs by international team of world-renowned experts in the field. The first fifteen chapters provide comprehensive and expert perspectives on the most common cancers from bench to bedside applications, there is no current book structured in this cancer-oriented way. The next seven chapters providing thorough overviews of miRNAs and cancer stem cells; miRNAs in cancer invasion and metastasis; miRNAs in predicting radiotherapy and chemotherapy response; as well as expounding the role of miRNA in anti-cancer drug resistance and as blood-based cancer biomarkers. Furthermore, this book explicates the interplay of miRNAs in cancer metabolism and an update on the pioneering RNAi-based treatment approaches is also presented.

This specialized book will contribute great to the scientific and medical community by providing the up-to-date discoveries of miRNAs and their important roles in cancer translational research.


Cancer Oncology Translational Research microRNAs small non-coding RNAs

Editors and affiliations

  • William C.S. Cho
    • 1
  1. 1., Department of Clinical OncologyQueen Elizabeth HospitalHong Kong SARChina, People's Republic

Bibliographic information

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From the reviews:

“The editor William C. S. Cho provides a comprehensive coverage and a succinct overview of the state-of-the-art knowledge on miRNA research … . a rich and thorough compendium uniting all relevant aspects of miRNA-stimulated translational cancer research. It covers … a proper spectrum of relevant topics and thus can be recommended for a broad scientific and medical readership. MCTR is a precious book for all types of readers: cancer researchers, oncologists, pathologists, biologists, clinical chemists, pharmacologists, and even bioinformaticians.” (Dominic Rose, Frontiers in Genetics, Vol. 3 (42), March, 2012)