CMOS Capacitive Sensors for Lab-on-Chip Applications

A Multidisciplinary Approach

  • Ebrahim Ghafar-Zadeh
  • Mohamad Sawan

Part of the Analog Circuits and Signal Processing book series (ACSP)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 1-23
  3. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 25-33
  4. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 35-50
  5. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 51-90
  6. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 91-118
  7. Ebrahim Ghafar-Zadeh, Mohamad Sawan
    Pages 119-126
  8. Back Matter
    Pages 127-142

About this book


Laboratory-on-Chip (LoC) is a multidisciplinary approach toward the miniaturization, integration and automation of biological assays. A biological laboratory contains various pieces of equipment used for performing a variety of biological protocols. The engineering aspect of LoC design is aiming to embed all these components in a single chip for single-purpose applications. LoC is a young discipline which is expected to subsequently expand over the next few years, stimulated by considerable development of applications in the mechanical, biochemical and electrical engineering domains. Among various microelectronic devices employed for LoC applications, CMOS capacitive sensors have received a significant interest for several applications including DNA detection, antibody-antigen recognition and bacteria growth monitoring. The main components of CMOS capacitive biosensors including sensing electrodes, bio-functionalized sensing layer, interface circuitries and microfluidic packaging are verbosely explained in chapters 2-6 after a brief introduction on CMOS based LoCs in Chapter 1. CMOS Capacitive Sensors for Lab-on-Chip Applications is written in a simple pedagogical way. It emphasises practical aspects of fully integrated CMOS biosensors rather than mathematical calculations and theoretical details. By using CMOS Capacitive Sensors for Lab-on-Chip Applications, the reader will have circuit design methodologies, main important biological capacitive interfaces and the required microfluidic fabrication procedures to create capacitive biosensor through standard CMOS process.


Bio-Engineering Biofunctionalized sensing layer Biosensor CMOS Capacitive sensor Lab-on-Chip Microfluidics integrated circuit

Authors and affiliations

  • Ebrahim Ghafar-Zadeh
    • 1
  • Mohamad Sawan
    • 2
  1. 1.Dept. Electrical & Computer EngineeringMcGill UniversityMontrealCanada
  2. 2.Dépt. Génie InformatiqueEcole Polytechnique de MontrealMontrealCanada

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