Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

A comprehensive review on their mode of action, treatment of abuse and intoxication

  • Enno Freye

Table of contents

  1. Front Matter
    Pages i-xi
  2. How It All Started with Cocaine

    1. Front Matter
      Pages 5-8
    2. Enno Freye
      Pages 1-3
    3. Enno Freye
      Pages 9-12
    4. Enno Freye
      Pages 13-18
    5. Enno Freye
      Pages 29-41
    6. Enno Freye
      Pages 49-60
    7. Enno Freye
      Pages 79-81
    8. Enno Freye
      Pages 87-97
  3. Methamphetamine-an Old Aquaintance in New Clothes

    1. Front Matter
      Pages 109-114
    2. Enno Freye
      Pages 115-117
    3. Enno Freye
      Pages 119-124
    4. Enno Freye
      Pages 125-129
    5. Enno Freye
      Pages 143-145
    6. Enno Freye
      Pages 147-149
    7. Enno Freye
      Pages 151-160
    8. Enno Freye
      Pages 161-172
    9. Enno Freye
      Pages 173-180
  4. MDMA (Ecstasy): from Psychotherapy to a Street Drug of Abuse

  5. Designer Drugs and their Abuse

    1. Front Matter
      Pages 182-182
  6. How to Demask the Patient with an Aberrant Drug Use

    1. Front Matter
      Pages 243-246

About this book


Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues.

The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance.

While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information.

As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation.

A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.


Cocaine Drugs Ecstasy Gamma-Hydroxybuturate (GHB) MDMA Methamphetamine amphetamine

Authors and affiliations

  • Enno Freye
    • 1
  1. 1.Neuss-UedesheimGermany

Bibliographic information

Industry Sectors
Health & Hospitals
Pharmacology & Toxicology
Consumer Packaged Goods