© 2000

Sepsis and Organ Dysfunction

The Challenge Continues

  • A. E. Baue
  • G. Berlot
  • A. Gullo
  • J.-L. Vincent
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-IX
  2. Introduction

    1. A. E. Baue
      Pages 11-15
  3. Sepsis and Organ Dysfunction. The Challenge Continues

    1. G. Berlot, U. Lucangelo, A. Gullo
      Pages 17-33
  4. Oxygen Transport in Sepsis

    1. Front Matter
      Pages 35-35
    2. A. Mayr, W. Pajk, W. Hasibeder
      Pages 43-48
    3. C. Adembri, A. R. De Gaudio, G. P. Novelli
      Pages 49-56
    4. W. Pajk, H. Knotzer, W. Hasibeder
      Pages 57-63
  5. Organ Dysfunction and Biohumoral Mismatch in Sepsis

    1. Front Matter
      Pages 65-65
    2. J. F. Pálizas
      Pages 67-76
    3. N. Latronico, G. F. Bussi, A. Candiani
      Pages 77-83
    4. J. A. Kellum
      Pages 91-101
    5. H. Zhang, C. Hsia, G. Porro
      Pages 107-112
  6. Sepsis Trial

    1. Front Matter
      Pages 113-113
    2. J.-L. Vincent
      Pages 115-121
    3. M. Meisner, K. Reinhart
      Pages 137-143

About these proceedings


An experienced physician knows how to recognize a patient suffering from sepsis, but cannot accurately determine whether the patient will survive. Cardinal elements of the treatment for sepsis include specific antibiotic and vasoactive drugs, enteral and parenteral nutrition, artificial respiration, and optimization of the oxygen transport to tissues. Nonetheless, with a certain frequency, these techniques are insufficient to ensure the recovery of a critically ill patient, especially when it is necessary to overcome functional alterations subsequent to organ and vital-system overload. The key elements in the progression of the sepsis-MODS syndrome are tied to numerous factors. These include: the severity and location of the lesion; the patient's age; the remaining functional reserve; the presence of mediatory which may be stimulatory, inhibitory or both.


Sepsis epidemiology pathophysiology respiration shock

Editors and affiliations

  • A. E. Baue
    • 1
  • G. Berlot
    • 2
  • A. Gullo
    • 2
  • J.-L. Vincent
    • 3
  1. 1.Department of Surgery, Health Sciences CenterSaint Louis UniversitySt. LouisUSA
  2. 2.Department of Anaesthesia, Intensive Care and Pain Therapy, Cattinara HospitalUniversity of TriesteTriesteItaly
  3. 3.Department of Intensive Care, Erasme University HospitalFree University of BrusselsBelgium

Bibliographic information

  • Book Title Sepsis and Organ Dysfunction
  • Book Subtitle The Challenge Continues
  • Editors A.E. Baue
    G. Berlot
    A. Gullo
    J.-L. Vincent
  • DOI
  • Copyright Information Springer-Verlag Milan 2000
  • Publisher Name Springer, Milano
  • eBook Packages Springer Book Archive
  • Softcover ISBN 978-88-470-0096-4
  • eBook ISBN 978-88-470-2284-3
  • Edition Number 1
  • Number of Pages IX, 168
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Intensive / Critical Care Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology