Contrast-Enhanced Ultrasound of Liver Diseases

  • Luigi Solbiati
  • Alberto Martegani
  • Edward Leen
  • Jean Michel Correas
  • Peter N. Burns
  • Dirk Becker

Table of contents

  1. Front Matter
    Pages I-XII
  2. P. N. Burns
    Pages 1-19
  3. A. Bauer, L. Solbiati
    Pages 21-26
  4. D. Becker
    Pages 27-36
  5. A. Martegani, L. Aiani, C. Borghi, L. Solbiati, M. Tonolini, A. Bellobuono et al.
    Pages 37-93
  6. E. Leen
    Pages 95-101
  7. L. Solbiati, M. Tonolini, L. Cova
    Pages 103-113
  8. J. M. Correas, O. Hélénon
    Pages 115-123

About this book


In the last few years, the development of sonographic contrast agents - or "microbubbles" - has stimulated increasingly intensive studies on the rela­ tionships between ultrasound and contrast media. As a result, "contrast -spe­ cific" hardware and software systems have been introduced by different ultra­ sound manufacturers with impressive speed. This has finally led to the birth of a very new imaging modality -"contrast-enhanced sonography" (CEUS). Since 1999, the introduction of second-generation contrast agents has represented a decisive step towards the extensive clinical use of CEUS and has simultaneously made obsolete most, if not all, scientific publications available so far. This book is, to our knowledge, the first to deal entirely with second­ generation contrast agents and the most updated contrast-specific software for noncardiologic uses. The reasons why the liver has been chosen as the only "target" of the book are easily understandable by radiologists and hepatologists alike. The study of vascularity is the only purpose of CEUS, and the liver has a unique vascular system, with two different inflow systems resulting in a single outflow. Furthermore, the pathologically different focal liver lesions (FLLs) are mostly characterized by different "models" of vascularity: CEUS can mimic contrast­ enhanced computed tomography and magnetic resonance imaging, basing differential diagnosis on the morphological and temporal characteristics of enhancement, but with the additional unique advantage of the study being done in real-time.


Contrast-enhanced sonography Focal Liver Lesions Hepatocellular carcinoma Radiofrequency ablation carcinoma cell imaging liver liver disease metastasis pharmacology sonography ultrasound

Authors and affiliations

  • Luigi Solbiati
    • 1
  • Alberto Martegani
    • 2
  • Edward Leen
    • 3
  • Jean Michel Correas
    • 4
  • Peter N. Burns
    • 5
  • Dirk Becker
    • 6
  1. 1.Dept. of RadiologyGeneral HospitalBusto Arsizio (VA)Italy
  2. 2.Servizio di RadiologiaOspedale ValduceComoItaly
  3. 3.Dept. of Radiology Royal InfirmaryUniversity of GlasgowGlasgowUK
  4. 4.Service de Radiologie AdulteHôpital Necker Enfants MaladesParis Cédex 15France
  5. 5.Depts. of Medical Biophysics and RadiologyUniversity of Toronto Sunnybrook and Women’s Health Sciences CentreCanada
  6. 6.Dept. of Medicine GastroenterologyIntensive Care Medicine Eckernförde Community HospitalEckernfördeGermany

Bibliographic information

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