Radiopharmaceuticals for Therapy

  • F. F. (Russ) Knapp
  • Ashutosh Dash

Table of contents

  1. Front Matter
    Pages i-xxiv
  2. Radiopharmaceuticals

    1. Front Matter
      Pages 1-1
    2. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 37-55
    3. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 57-67
  3. Production, Processing and Availability of Therapeutic Radioisotopes

    1. Front Matter
      Pages 69-69
    2. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 71-113
    3. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 115-129
  4. Therapeutic Radiopharmaceuticals for Cancer Therapy

    1. Front Matter
      Pages 167-167
    2. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 169-184
    3. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 185-207
  5. Therapeutic Radiopharmaceuticals for Treatment of Chronic Disease

    1. Front Matter
      Pages 223-223
    2. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 225-252
    3. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 253-264
    4. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 265-278
    5. F. F. (Russ) Knapp, Ashutosh Dash
      Pages 279-291
  6. Looking Ahead: New Radiopharmaceutical Strategies for Therapeutic Applications

  7. Back Matter
    Pages 345-347

About this book


This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation.  Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy.  In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.


Molecular nuclear medicine Nuclear medicine Protontherapy Radionuclide therapy Therapeutic radiopharmaceuticals

Authors and affiliations

  • F. F. (Russ) Knapp
    • 1
  • Ashutosh Dash
    • 2
  1. 1.Nuclear Security and Isotope DivisionOak Ridge National LaboratoryOAK RIDGEUSA
  2. 2.Isotope Production and Applications DivnBhabha Atomic Research CentreMumbaiIndia

Bibliographic information

  • DOI
  • Copyright Information Springer India 2016
  • Publisher Name Springer, New Delhi
  • eBook Packages Medicine
  • Print ISBN 978-81-322-2606-2
  • Online ISBN 978-81-322-2607-9
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Nuclear Medicine