Portal Hypertension

Clinical and Physiological Aspects

  • Kunio Okuda
  • Jean-Pierre Benhamou

Table of contents

  1. Front Matter
    Pages I-XIX
  2. Pathophysiology

    1. Front Matter
      Pages 1-1
    2. P. Bioulac-Sage, J. Saric, C. Balabaud
      Pages 13-26
    3. Thomas C. Mahl, Roberto J. Groszmann
      Pages 27-33
    4. Miquel Navasa, Jaime Bosch, Joan Rodés
      Pages 35-49
    5. Kunio Okuda, Shoichi Matsutani
      Pages 51-62
    6. Soichiro Miura, Masaharu Tsuchiya
      Pages 63-84
    7. Gilles A. Morali, Laurence M. Blendis
      Pages 85-99
    8. Didier Lebrec
      Pages 101-113
  3. Hemodynamic Investigations

    1. Front Matter
      Pages 115-115
    2. Didier Lebrec
      Pages 117-125
    3. Jaime Bosch, Faust Feu, Joan-Carles García-Pagán
      Pages 139-150
    4. Fuminori Moriyasu
      Pages 151-159
    5. Luigi Bolondi, Stefano Gaiani, Luigi Barbara
      Pages 161-182
    6. Kunio Okuda, Susumu Shiomi
      Pages 183-194
  4. Imaging Investigations

    1. Front Matter
      Pages 195-195
    2. Shoichi Matsutani, Kunio Kimura, Masao Ohto, Kunio Okuda
      Pages 197-206
    3. Kunio Okuda, Kenichi Takayasu
      Pages 219-229
    4. Kunio Okuda, Kenichi Takayasu
      Pages 231-237
  5. Clinical and Pathophysiological Features

    1. Front Matter
      Pages 239-239
    2. Antoine Hadengue, Didier Lebrec, Jean-Pierre Benhamou
      Pages 241-249
    3. Hyman J. Zimmerman, James H. Lewis, Chris Kassianides
      Pages 251-270
    4. Kunio Okuda, Hiroshi Obata
      Pages 271-287
    5. Masayoshi Kage, Toshiro Nakashima
      Pages 289-299
    6. Kunio Okuda, Masahiko Iuchi
      Pages 301-307
    7. Luiz Caetano Da Silva
      Pages 309-318
    8. Telfer B. Reynolds
      Pages 319-323
    9. Pauline de la M. Hall
      Pages 343-361
    10. Jean-Pierre Benhamou
      Pages 363-364
    11. Kunio Okuda, Haruo Aoki
      Pages 365-379
    12. Jean-Pierre Benhamou, Dominique Valla
      Pages 381-392
    13. I. R. Wanless
      Pages 393-399
    14. Antoine Hadengue, Didier Lebrec, Jean-Pierre Benhamou
      Pages 401-411
  6. Esophageal Varices and Gastrointestinal Bleeding

    1. Front Matter
      Pages 413-413
    2. Masahiro Arakawa, Masayoshi Kage
      Pages 415-428
    3. Kunio Okuda, Kenichi Takayasu
      Pages 429-440
    4. David R. Triger
      Pages 441-452
    5. Fabrizio Cardin, P. Aiden McCormick, Andrew K. Burroughs
      Pages 453-464
    6. Karl-Joseph Paquet
      Pages 495-507
    7. Henri Bismuth, David J. Sherlock, René Adam
      Pages 519-531
    8. David H. Van Thiel
      Pages 549-554
    9. Didier Lebrec, Jean-Pierre Benhamou
      Pages 555-561

About this book


Portal hypertension is the abnormal pathophysiologic state that develops in liver cirrhosis and certain other disorders with characteristic clinical and hemodynamic features. There has been great progress in our under­ standing and management of portal hypertension, particularly in the diagnostic and therapeutic approaches. The so-called Banti's syndrome, a disorder whose existence had long been questioned, is now a well-defined portal hypertensive disease. The recently introduced Doppler ftowmetry is currently yielding new information on portal hemodynamics. Endoscopic sclerotherapy and beta-blockers have come to be widely used in the man­ agement and prevention of variceal bleeding. In spite of all these advances, a number of unsolved questions remain, such as whether sclerotherapy, pharmacotherapy or surgery is warranted for prevention of bleeding, which is more effective as an elective treatment, the surgical or endoscopic approach, and whether surgical portacaval shunt should be totally replaced by selective shunt operations. These new developments and problems are clearly and comprehensively described and discussed by the foremost authorities in 44 chapters, which are divided into five sections: 1) Patho­ physiology, 2) Hemodynamic Investigations, 3) Imaging Investigations, 4) Clinical and Pathological Features, and 5) Esophageal and Gastrointestinal Bleeding. The primary goal of this monograph, to provide a framework of patho­ physiology of portal hypertension with authoritative descriptions of the clinical and laboratory manifestations of various portal hypertensive dis­ orders, has clearly been achieved by these excellent contributions.


Portal hemodynamics Portal hypertension Portal-systemic collateral Sclerotherapy Varices Banti's syndrome cirrhosis endoscopy hemodynamics hypertension imaging liver physiology portal hypertension shunt surgery

Editors and affiliations

  • Kunio Okuda
    • 1
  • Jean-Pierre Benhamou
    • 2
  1. 1.Department of MedicineChiba University HospitalChiba, 280Japan
  2. 2.Department of HepatologyHopital BeaujonClichyFrance

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