Advertisement

Recent Progress in Failing Heart Syndrome

  • Shigetake Sasayama
  • Hiroyuki Suga

Table of contents

  1. Front Matter
    Pages I-IX
  2. Seiryo Sugiura, Hiroshi Yamashita, Takashi Serizawa, Masahiko Iizuka
    Pages 1-18
  3. Yoshio Yazaki, Masahiko Kurabayashi, Issei Komuro
    Pages 19-41
  4. Masatsugu Hori, Yukihiro Koretsune, Masafumi Kitakaze, Hideo Kusuoka, Eduardo Marban, Michitoshi Inoue
    Pages 43-60
  5. Keijiro Kusunoki, Yasuyuki Nakamura, Takashi Konishi, Masato Matsunaga, Chuichi Kawai
    Pages 151-160
  6. Kenji Sunagawa, Kiyoshi Hayashida, Masaru Sugimachi, Koji Todaka, Toru Kubota, Ryoichi Itaya et al.
    Pages 161-185
  7. Shigetake Sasayama, Hidetsugu Asanoi
    Pages 187-220
  8. Masatsugu Hori, Toshifumi Kagiya, Hideyuki Sato, Hiroshi Sato, Akira Kitabatake, Masatake Fukunami et al.
    Pages 221-240
  9. Yasuyuki Nakamura, Takashi Konishi, Toshiaki Kumada, Chuichi Kawai
    Pages 241-255
  10. Motoaki Sugawara, Kiyoharu Nakano, Masatoshi Kawana, Jun Umemura, Shigetake Sasayama, Blase A. Carabello
    Pages 257-279
  11. Teruyuki Yanagisawa, Kuniaki Ishii, Hitoshi Yokoyama, Hideo Kurosawa, Norio Taira
    Pages 281-302
  12. Takeshi Nakatani, Hisateru Takano, Hiroyuki Noda, Masayuki Kinoshita
    Pages 325-339
  13. Back Matter
    Pages 341-344

About this book

Introduction

Heart failure is a syndrome caused by a heart dysfunction that leads to insuf­ ficient blood in the peripheral tissues for their metabolic demands. This syn­ drome still remains an obscure clinical entity and even its definition is disputed. It has become increasingly apparent that heart failure may relate not only to cardiac dysfunction but also to other physiological alterations involved in the maintenance of circulatory homeostasis. In 1988, the Japanese Circulation Society organized a three-year project for research on heart failure. The research group consisted of ten investigators, all relatively young but well recognized internationally for their research accomplishments. This book represents a compilation of the achievements by this group during the past three years which have led to new insights into the pathophysiologic mechanisms of heart failure, and diagnosis, evaluation and treatment of this syndrome. Contents include research into the cellular biology of congestive heart failure, and a framework of pressure-volume relationships enabling assessment of ventricular contraction energetics or coupling of ventricular properties and arterial load. This conceptual framework is of vital significance, particularly when we consider the failing heart as an energy-depleted state. An understanding of the neuroendocrine responses to explain the pathophy­ siology of congestive heart failure is perhaps the most important advance, and has led to new developments in therapy. This book also includes an analysis of mechanical factors, including both regional, and global ventricular functions, and this is related to the under­ standing of the pathophysiology of congestive heart failure.

Keywords

adaptation artery biology circulation heart heart failure myocardial infarction physiology stroke

Editors and affiliations

  • Shigetake Sasayama
    • 1
  • Hiroyuki Suga
    • 2
  1. 1.The Second Department of Internal MedicineToyama Medical and Pharmaceutical UniversityToyamaJapan
  2. 2.Okayama University Medical SchoolOkayamaJapan

Bibliographic information

Industry Sectors
Pharma
Health & Hospitals
Biotechnology