© 1995

Regulation of the Contractile Cycle in Smooth Muscle

  • Takeshi Nakano
  • David J. Hartshorne
Conference proceedings

Table of contents

  1. Front Matter
    Pages II-VIII
  2. A. V. Somlyo, E. Nishiye, A. Khromov, A. P. Somlyo
    Pages 73-84
  3. John Kendrick-Jones, Tony Rowe, Ana C. Rasera da Silva, Fernando C. Reinach
    Pages 111-130
  4. Satoshi Matsushima, Masaaki Ito, David J. Hartshorne, Vince Guerriero Jr.
    Pages 131-137
  5. Kristine E. Kamm, Katherine Luby-Phelps, Malu G. Tansey, Patricia J. Gallagher, James T. Stull
    Pages 139-158
  6. Li-Hong Ye, Kohichi Hayakawa, Tsuyoshi Okagaki, Kazuhiro Kohama
    Pages 159-173
  7. A. P. Somlyo, M. Gong, K. Iizuka, T. Haystead, A. V. Somlyo
    Pages 175-185
  8. Masaaki Ito, Hiroyuki Shimizu, Masatoshi Miyahara, Jian-Hua Feng, Setsuya Okubo, Kazuhito Ichikawa et al.
    Pages 187-200
  9. Katsuhito Takahashi, Hiroaki Masuda, Michiko Takagi, Yoshimi Eshita, Nobuhiko Shibata
    Pages 201-209
  10. Toshio Tanaka, Michiko Naka, Terumasa Mino, Uhito Yuasa, Fumiaki Nakamura, Junichi Yamamoto et al.
    Pages 211-221
  11. Ryozo Nagai, Masanori Aikawa, Makoto Kuro-o, Ichiro Manabe, Yasunari Sakomura, Masafumi Watanabe et al.
    Pages 223-232
  12. Back Matter
    Pages 233-239

About these proceedings


At the Mie International Symposium held in Japan in April 1994, leading scientists reviewed recent advances in the understanding of the contractile mechanism in smooth muscle. The present volume collects the papers presented at the symposium, summarizing the latest advances in smooth muscle function and emphasizing important components of the contraction-relaxation cycle. Topics include a discussion of the smooth muscle cell membrane, with emphasis on its ion channels; the regulation of cytosolic Ca2+ levels and the relationship to force in smooth muscle; aspects of the two key regulatory enzymes involved with myosin phosphorylation-dephosphorylation; the molecular basis for pharmacomechanical coupling in smooth muscle; developments in the basic contractile mechanisms involving the crossbridge cycle of tonic and phasic muscle; the role of myosin light chains; and many others. The approach is broad and presents contemporary opinions in pharmacology, physiology, and biochemistry as they relate to smooth muscle function. The book will appeal not only to those working in these disciplines, but to vascular clinicians, obstetric-gynecological physicians, and gastroenterologists as well.


Ca2+ transients Contractile Cycle contraction-relaxation cycle ion channels physiology regulation smooth muscle

Editors and affiliations

  • Takeshi Nakano
    • 1
  • David J. Hartshorne
    • 2
  1. 1.Mie University of School MedicineMieJapan
  2. 2.University of ArizonaTucsonUSA

Bibliographic information

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