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Evolution of the Human Genome I

The Genome and Genes

  • Naruya¬†Saitou

Part of the Evolutionary Studies book series (EVOLUS)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Overview of the Human Genome

    1. Front Matter
      Pages 1-1
    2. Satoshi Oota
      Pages 61-92
    3. Tadashi Imanishi
      Pages 93-116
    4. Takashi Kitano
      Pages 117-130
    5. Ludovica Montanucci, Jaume Bertranpetit
      Pages 131-142
    6. Naoko Takezaki
      Pages 143-155
  3. The Human Genome Viewed Through Genes

    1. Front Matter
      Pages 157-157
    2. Yoko Satta, Yukako Katsura, Mineyo Iwase
      Pages 159-172
    3. Shoji Kawamura, Amanda D. Melin
      Pages 181-216
    4. Mahoko Ueda Takahashi, So Nakagawa
      Pages 241-263
    5. Ituro Inoue, Hirofumi Nakaoka
      Pages 265-272
    6. Chaochun Wei, Ben Jia
      Pages 285-300
  4. Back Matter
    Pages 301-305

About this book

Introduction

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.

Keywords

Human genome Evolution Primates Disease Genome organization Transcription factors Opsin genes Junk DNA Recombination

Editors and affiliations

  • Naruya¬†Saitou
    • 1
  1. 1.Division of Population GeneticsNational Institute of GeneticsMishimaJapan

Bibliographic information

  • DOI https://doi.org/10.1007/978-4-431-56603-8
  • Copyright Information Springer Japan KK 2017
  • Publisher Name Springer, Tokyo
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-4-431-56601-4
  • Online ISBN 978-4-431-56603-8
  • Series Print ISSN 2509-484X
  • Series Online ISSN 2509-4858
  • Buy this book on publisher's site
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