Adult T-cell Leukemia/Lymphoma

  • Toshiki Watanabe
  • Takuya Fukushima

Table of contents

  1. Front Matter
    Pages i-viii
  2. Toshiki Watanabe, Takuya Fukushima
    Pages 1-2
  3. Jun-ichi Fujisawa
    Pages 3-31
  4. Masako Iwanaga
    Pages 33-48
  5. Koichi Ohshima, Hiroaki Miyoshi
    Pages 49-65
  6. Kaoru Uchimaru
    Pages 67-81
  7. Takuya Fukushima
    Pages 109-116
  8. Wataru Munakata, Kensei Tobinai
    Pages 145-155

About this book


This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.


ATL Anti-CCR4 antibody HTLV-1 Human T-lymphotropic Virus Type-I agressive ATL

Editors and affiliations

  • Toshiki Watanabe
    • 1
  • Takuya Fukushima
    • 2
  1. 1.Department of Medical Genome Sciences Graduate School of Frontier SciencesThe University of TokyoTokyoJapan
  2. 2.Department of Clinical Laboratory Sciences School of Health SciencesUniversity of the RyukyusOkinawaJapan

Bibliographic information

Industry Sectors
Health & Hospitals
Oncology & Hematology