© 2017

Neuroimaging Diagnosis for Alzheimer's Disease and Other Dementias

  • Hiroshi Matsuda
  • Takashi Asada
  • Aya Midori Tokumaru

Table of contents

  1. Front Matter
    Pages i-viii
  2. Takashi Asada
    Pages 1-10
  3. Hiroshi Matsuda, Etsuko Imabayashi
    Pages 21-38
  4. Aya M. Tokumaru, Yuko Saito, Shigeo Murayama, Keita Sakurai
    Pages 39-115
  5. Toshiaki Taoka
    Pages 117-128
  6. Takashi Yoshiura
    Pages 129-138
  7. Yoshitaka Inui, Kengo Ito, Takashi Kato
    Pages 189-198
  8. Nobuyuki Okamura, Ryuichi Harada, Shozo Furumoto, Yukitsuka Kudo
    Pages 199-210
  9. Kiyotaka Nemoto
    Pages 211-220
  10. Haruo Hanyu
    Pages 221-231
  11. Miharu Samuraki, Ichiro Matsunari, Masahito Yamada
    Pages 243-255
  12. Norihide Maikusa
    Pages 257-267

About this book


This book describes the latest modalities such as tau PET imaging for diagnosis of Alzheimer’s disease and other dementias, and also provides information on handling and analyzing imaging data that is not found in other books. In addition, it introduces routine imaging studies in the management of dementia in Japan. The prevalence of dementia has increased over the past few decades, either because of greater awareness and more accurate diagnosis, or because increased longevity has created a larger population of the elderly, the age group most commonly affected. Although only clinical assessment can lead to a diagnosis of dementia, neuroimaging in dementia is recommended by most clinical guidelines, and its adjunct role has traditionally been to exclude a mass lesion rather than to support a specific diagnosis. Neuroimaging may be also helpful for developing new strategies to achieve diagnoses as early as possible for therapies aimed at slowing the progression of neurodegenerative diseases manifesting dementia. Under these conditions, all clinicians and researchers who are involved in neuroimaging for dementia should decide which patients to scan, when imaging patients is most useful, which modality to use, how to handle imaging data from many institutions, and which analytical tool to use. This edition comprises contributions from leading Japanese experts in their fields.


Alzheimer dementia imaging for diagnosis neuroimaging tau PET

Editors and affiliations

  • Hiroshi Matsuda
    • 1
  • Takashi Asada
    • 2
  • Aya Midori Tokumaru
    • 3
  1. 1.Integrative Brain Imaging Center, National Center of Neurology & PsychiatryKodairaJapan
  2. 2.Department of Psychiatry, Institute of Clinical MedicineUniversity of TsukubaTsukubaJapan
  3. 3.Department of Diagnostic RadiologyTokyo Metropolitan Geriatric Hospital and Institute of GerontologyTokyoJapan

About the editors

Hiroshi Matsuda Integrative Brain Imaging Center, National Center of Neurology and Psychiatry 
Takashi Asada Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba 
Aya Midori Tokumaru Department of Diagnostic Radiology, Tokyo Metropolitan Medical Centre of Gerontology

Bibliographic information

Industry Sectors
Health & Hospitals


“I enjoyed reading this book and will keep it available in our department for teaching and as a useful reference. … The illustrations and neuro-imaging are generally of a high standard. This book is likely to be of interest to a wide range of readers, clinicians, clinical radiologists and anyone commencing research in dementia.” (Andrew D MacKinnon, RAD Magazine, October, 2018)

“This is a guide to aid researchers and clinicians in decision making and analysis of imaging for Alzheimer's disease and related dementias. … The audience is anyone involved in clinical care or research where imaging is needed. … The authors are well respected experts in their areas. ... The images are of high quality and are discussed explicitly.” (Carol Lippa, Doody's Book Reviews, February, 2018)