© 2011

Neurogenesis in the Adult Brain I


  • Tatsunori Seki
  • Kazunobu Sawamoto
  • Jack M. Parent
  • Arturo Alvarez-Buylla

Table of contents

  1. Front Matter
    Pages i-xv
  2. History

  3. Basic Aspects of Neurogenesis

    1. Front Matter
      Pages 85-85
    2. Masakazu Namihira, Kinichi Nakashima
      Pages 87-107
    3. Frederic Mercier, Jason Schnack, Maureen Saint Georges Chaumet
      Pages 109-133
  4. Adult Neurogenesis in Non-mammalian Vertebrates

    1. Front Matter
      Pages 135-135
    2. Günther K. H. Zupanc
      Pages 137-167
    3. Susana González-Granero, Melissa Lezameta, José Manuel García-Verdugo
      Pages 169-189
  5. Adult Neurogenesis in the Hippocampus

    1. Front Matter
      Pages 191-191
    2. Tatsuhiro Hisatsune, Yoko Ide, Rokuya Nochi
      Pages 217-236
    3. Wei Deng, Chunmei Zhao, Fred H. Gage
      Pages 237-255
  6. Adult Neurogenesis in the Olfactory Bulb

    1. Front Matter
      Pages 285-285
    2. Zaman Mirzadeh, Young-Goo Han, José Manuel García-Verdugo, Arturo Alvarez-Buylla
      Pages 287-317
    3. Giovanna Ponti, Federico Luzzati, Paolo Peretto, Luca Bonfanti
      Pages 319-336
    4. Masato Sawada, Shi-hui Huang, Yuki Hirota, Naoko Kaneko, Kazunobu Sawamoto
      Pages 337-355

About this book


The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.

Editors and affiliations

  • Tatsunori Seki
    • 1
  • Kazunobu Sawamoto
    • 2
  • Jack M. Parent
    • 3
  • Arturo Alvarez-Buylla
    • 3
  1. 1.Department of Histology and NeuroanatomyTokyo Medical UniversityTokyoJapan
  2. 2.Department of Developmental and Regenerative BiologyInstitute of Molecular Medicine Nagoya City University Graduate School of Medical SciencesNagoyaJapan
  3. 3.Department of NeurologyUniversity of MichiganAnn ArborUSA

Bibliographic information

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