© 2014

Developmental Aspects of the Lymphatic Vascular System

  • Friedemann Kiefer
  • Stefan Schulte-Merker


  • Unique book on the market explaining the development of the lymphatic vascular system

  • Assembles international experts in this field

  • Describes in a concise and clear way novel research findings and their methods ?


Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 214)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Friedemann Kiefer, Stefan Schulte-Merker
    Pages 1-4
  3. Lara Planas-Paz, Eckhard Lammert
    Pages 23-40
  4. Li-Chin Yao, Donald M. McDonald
    Pages 41-54
  5. Sophie Lutter, Taija Makinen
    Pages 55-65
  6. Serge A. van de Pavert, Reina E. Mebius
    Pages 81-91
  7. Steve P. Watson, Kate Lowe, Brenda A. Finney
    Pages 93-105
  8. Raghu P. Kataru, Yulia G. Lee, Gou Young Koh
    Pages 107-118
  9. Alexandra M. Ochsenbein, Sinem Karaman, Giorgia Jurisic, Michael Detmar
    Pages 143-152
  10. Andreas van Impel, Stefan Schulte-Merker
    Pages 153-165
  11. Cathrin Pollmann, René Hägerling, Friedemann Kiefer
    Pages 167-186
  12. Carlo Bellini, Raoul CM Hennekam
    Pages 187-204

About this book


For decades, lymphatic vessels were considered to be of “lesser significance” than blood vessels, and the fundamental importance of lymphatic vessels for physiological tissue homeostasis and their involvement in many pathological processes have only recently been fully appreciated. It is clear by now that all higher vertebrates possess a lymphatic vessel system, and that malfunctioning of the lymphatic vasculature has severe pathophysiological consequences.

Still, many central aspects of the developmental origin, growth control and regulation of lymphatic vessels are not sufficiently understood. This volume of “Advances in Anatomy, Embryology, and Cell Biology” focuses on the lymphatic vascular system from a developmental point of view, presenting exciting recent advances in elucidating the development and molecular control of lymphatic vessels. A collection of focused reviews, written by respected experts, describes ostensively how advanced genetic models and state-of-the-art imaging are being used to decipher the action of transcriptional programs, growth factors and matrix components in the regulation of lymphatic endothelial cell behavior. A synopsis is provided for each chapter, concisely highlighting the main points.

This collection provides both an ideal introduction to lymph vessel biology for newcomers and an invaluable resource for experts.


Lymph nodes Lymph vessels Lymphangiogenesis Lymphatic endothelial cell Lymphatics

Editors and affiliations

  • Friedemann Kiefer
    • 1
  • Stefan Schulte-Merker
    • 2
  1. 1.MPI for Molecular BiomedicineMünsterGermany
  2. 2.Hubrecht InstituteUtrechtThe Netherlands

About the editors

Friedemann Kiefer is group leader at the Max Planck Institute for Molecular Biomedicine in Münster, Germany and Adjunct Professor at the Medical Faculty of the University of Münster. Stefan Schulte-Merker is group leader and Professor of Molecular Developmental Biology at the Hubrecht Institute in Utrecht, The Netherlands.

Bibliographic information

  • Book Title Developmental Aspects of the Lymphatic Vascular System
  • Editors Friedemann Kiefer
    Stefan Schulte-Merker
  • Series Title Advances in Anatomy, Embryology and Cell Biology
  • Series Abbreviated Title Advs Anatomy
  • DOI
  • Copyright Information Springer-Verlag Wien 2014
  • Publisher Name Springer, Vienna
  • eBook Packages Medicine Medicine (R0)
  • Softcover ISBN 978-3-7091-1645-6
  • eBook ISBN 978-3-7091-1646-3
  • Series ISSN 0301-5556
  • Series E-ISSN 2192-7065
  • Edition Number 1
  • Number of Pages XII, 204
  • Number of Illustrations 0 b/w illustrations, 27 illustrations in colour
  • Topics Human Physiology
    Cell Biology
    Developmental Biology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals