Sphingolipids in Disease

  • Erich Gulbins
  • Irina Petrache

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 216)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Sphingolipids in Cancer

    1. Front Matter
      Pages 1-1
    2. Guoqiang Hua, Richard Kolesnick
      Pages 29-54
    3. Marie-Thérèse Dimanche-Boitrel, Amélie Rebillard
      Pages 73-91
    4. Tzipora Goldkorn, Samuel Chung, Simone Filosto
      Pages 93-113
    5. Carla Hajj, Adriana Haimovitz-Friedman
      Pages 115-130
  3. Sphingolipids in Cardio-Reno-vascular Diseases

  4. Sphingolipids in Inflammation, Infection and Lung Diseases

    1. Front Matter
      Pages 199-199
    2. Stefan Uhlig, Yang Yang
      Pages 227-246
    3. Irina Petrache, Daniela N. Petrusca
      Pages 247-264
    4. Heike Grassmé, Joachim Riethmüller, Erich Gulbins
      Pages 265-274
    5. K. Alexa Orr Gandy, Lina M. Obeid
      Pages 275-303
    6. Heike Grassmé, Katrin Anne Becker
      Pages 305-320
    7. Jürgen Schneider-Schaulies, Sibylle Schneider-Schaulies
      Pages 321-340
    8. Annette Draeger, Eduard B. Babiychuk
      Pages 341-353
    9. Burkhard Kleuser, Lukasz Japtok
      Pages 355-372
    10. S. B. Russo, J. S. Ross, L. A. Cowart
      Pages 373-401
  5. Sphingolipids in Neuro-psychiatry and Muscle Diseases

    1. Front Matter
      Pages 403-403
    2. Einat B. Vitner, Anthony H. Futerman
      Pages 405-419
    3. Laura Davies, Klaus Fassbender, Silke Walter
      Pages 421-430
    4. C. Mühle, M. Reichel, E. Gulbins, J. Kornhuber
      Pages 431-456
    5. Paola Bruni, Chiara Donati
      Pages 457-467
  6. Back Matter
    Pages 469-478

About this book


Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This  book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology  as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease.   ​


Cancer Ceramide Infectious Disease Sphingolipids Sphingosine 1-Phosphate Sphingosine Kinase

Editors and affiliations

  • Erich Gulbins
    • 1
  • Irina Petrache
    • 2
  1. 1., Department of Molecular BiologyUniversity of Duisburg-EssenEssenGermany
  2. 2.Division of Pulmonary, Allergy, Critical, Department of MedicineIndiana University School of MedicineIndianapolisUSA

Bibliographic information

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